Evidence map›Paper›PMID 38136280›Full record

ArticleCancers2023

Urinary, Gastrointestinal, and Sexual Dysfunctions after Chemotherapy, Radiotherapy, Radical Surgery or Multimodal Treatment in Women with Locally Advanced Cervical Cancer: A Multicenter Retrospective Study.

Mariano Catello Di Donna, Giuseppe Cucinella, Vincenzo Giallombardo, Giulio Sozzi, Nicolò Bizzarri, Giovanni Scambia, Basilio Pecorino, Paolo Scollo, Roberto Berretta, Vito Andrea Capozzi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Revealing relationships: The role of self-disclosure and marital intimacy in the post-traumatic growth of cervical cancer patients-A qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Da VinciAnnals of surgical oncology · 2025
    Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Mariano Catello Di DonnaUnit of Gynecologic Oncology, ARNAS "Civico-Di Cristina-Benfratelli", 90127 Palermo, Italy.
Giuseppe CucinellaDepartment of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), University of Palermo, 90133 Palermo, Italy.ORCID 0000-0001-8574-7346
Vincenzo GiallombardoUnit of Gynecologic Oncology, ARNAS "Civico-Di Cristina-Benfratelli", 90127 Palermo, Italy.
Giulio SozziDepartment of Obstetrics and Gynecology, Fondazione Istituto G. Giglio, 90015 Cefalù, Italy.ORCID 0000-0001-5847-8822
Nicolò BizzarriGynecologic Oncology Unit, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 1, 00168 Rome, Italy.ORCID 0000-0002-1727-904X
Giovanni ScambiaGynecologic Oncology Unit, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 1, 00168 Rome, Italy.
Basilio PecorinoMaternal and Child Department, Obstetrics and Gynecology, Cannizzaro Hospital, 95100 Catania, Italy.ORCID 0000-0001-6987-4193
Paolo ScolloMaternal and Child Department, Obstetrics and Gynecology, Cannizzaro Hospital, 95100 Catania, Italy.ORCID 0000-0001-6275-7488
Roberto BerrettaDepartment of Obstetrics and Gynecology, University of Parma, 43125 Parma, Italy.
Vito Andrea CapozziDepartment of Obstetrics and Gynecology, University of Parma, 43125 Parma, Italy.ORCID 0000-0003-4720-5663
Antonio Simone LaganàUnit of Obstetrics and Gynecology, "Paolo Giaccone" Hospital, 90127 Palermo, Italy.ORCID 0000-0003-1543-2802
Vito ChianteraGynecologic Oncology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Naples, Italy.
Agostino Gemelli University Polyclinic · ITAzienda di Rilievo Nazionale ed Alta Specializzazione · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversità degli Studi di Enna Kore · ITUniversity of Parma · ITAzienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifferent strategies have been proposed for the treatment of locally advanced cervical cancer (LACC), with different impacts on patient's quality of life (QoL). This study aimed to analyze urinary, bowel, and sexual dysfunctions in a series of LACC patients who underwent chemotherapy, radiotherapy, radical surgery, or a combination of these treatments.

methodsPatients with LACC who underwent neoadjuvant radio-chemotherapy (NART/CT;

resultsA total of 90 patients were included. Increased urinary frequency (>8 times/day) was higher in ERT/CT compared with NACT/RT (57.1% vs. 28.6%;

conclusionsThe rate and severity of urinary, gastrointestinal, and sexual dysfunction were similar in the four groups of treatment. Nevertheless, ERT/CT was associated with worse sexual and urinary outcomes.

Indexed as

cervical cancerchemotherapymultimodal treatmentsneoadjuvant concurrent chemoradiationpatient-reported outcomesquality of liferadical surgeryradiotherapy

Identifiers

PMID38136280
PMCPMC10741503
OpenAlexW4389452150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.