Evidence map›Paper›PMID 38135904›Full record

ArticleMolecular oncology2024

Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023.

Ulrik Ringborg, Joachim von Braun, Julio Celis, Michael Baumann, Anton Berns, Alexander Eggermont, Edith Heard, Manuel Heitor, Mammen Chandy, Chien-Jen Chen and 27 more

Abstract read
In one paragraph

Article in Molecular oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Ulrik RingborgEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Joachim von BraunPontifical Academy of Sciences, Vatican City, Italy.
Julio CelisEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Michael BaumannEuropean Academy of Cancer Sciences, Stockholm, Sweden.ORCID 0000-0002-9340-974X
Anton BernsEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Alexander EggermontEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Edith HeardPontifical Academy of Sciences, Vatican City, Italy.
Manuel HeitorEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Mammen ChandyTata Medical Center, Kolkata, India.
Chien-Jen ChenPontifical Academy of Sciences, Vatican City, Italy.
Alberto CostaEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Francesco De LorenzoEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Edward M De RobertisPontifical Academy of Sciences, Vatican City, Italy.
Frederick Charles DubeeBeijing Genomics Institute (BGI), Helsinki, Finland.
Ingemar ErnbergKarolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-6518-1648
Mariya GabrielEuropean Commissioner for Innovation, Research, Culture, Education and Youth, Brussels, Belgium.
Åslaug HellandDivision for Cancer Medicine, Oslo University Hospital, Norway.
Rui HenriquePorto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), Portugal.ORCID 0000-0003-3171-4666
Bengt JönssonEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Olli KallioniemiEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Jan KorbelEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Mechthild KrauseEuropean Academy of Cancer Sciences, Stockholm, Sweden.ORCID 0000-0003-1776-9556
Douglas R LowyNational Cancer Institute, Bethesda, MD, USA.
Olivier MichielinCHUV Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Peter NagyEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Simon OberstOrganisation of European Cancer Institutes, Brussels, Belgium.ORCID 0000-0002-1139-2578
Vincenzo PagliaPontifical Academy for Life, Rome, Italy.
M Iqbal ParkerUniversity of Cape Town and African Academy of Sciences, South Africa.ORCID 0000-0001-7087-3825
Kevin RyanEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Charles L SawyersMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Joachim SchüzEuropean Academy of Cancer Sciences, Stockholm, Sweden.ORCID 0000-0001-9687-2134
Katherine SilkaitisEuropean Molecular Biology Laboratory, Heidelberg, Germany.
Eric SolaryEuropean Academy of Cancer Sciences, Stockholm, Sweden.ORCID 0000-0002-8629-1341
David ThomasGarvan Institute of Medical Research, The Kinghorn Cancer Centre, Sydney, Australia.
Peter TurksonPontifical Academy of Sciences, Vatican City, Italy.
Elisabete WeiderpassEuropean Academy of Cancer Sciences, Stockholm, Sweden.
Huanming YangBeijing Genomics Institute (BGI), Shenzhen, China.

Funding

Tumor gene expression in vitro and in vivoZIABC008905 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LOWY, DOUGLAS R. · 2009 to 2025
$14.3M
Cancer Research UK 15816World Health Organization 001
6 · The paper itself

Abstract

Analyses of inequalities related to prevention and cancer therapeutics/care show disparities between countries with different economic standing, and within countries with high Gross Domestic Product. The development of basic technological and biological research provides clinical and prevention opportunities that make their implementation into healthcare systems more complex, mainly due to the growth of Personalized/Precision Cancer Medicine (PCM). Initiatives like the USA-Cancer Moonshot and the EU-Mission on Cancer and Europe's Beating Cancer Plan are initiated to boost cancer prevention and therapeutics/care innovation and to mitigate present inequalities. The conference organized by the Pontifical Academy of Sciences in collaboration with the European Academy of Cancer Sciences discussed the inequality problem, dependent on the economic status of a country, the increasing demands for infrastructure supportive of innovative research and its implementation in healthcare and prevention programs. Establishing translational research defined as a coherent cancer research continuum is still a challenge. Research has to cover the entire continuum from basic to outcomes research for clinical and prevention modalities. Comprehensive Cancer Centres (CCCs) are of critical importance for integrating research innovations to preclinical and clinical research, as for ensuring state-of-the-art patient care within healthcare systems. International collaborative networks between CCCs are necessary to reach the critical mass of infrastructures and patients for PCM research, and for introducing prevention modalities and new treatments effectively. Outcomes and health economics research are required to assess the cost-effectiveness of new interventions, currently a missing element in the research portfolio. Data sharing and critical mass are essential for innovative research to develop PCM. Despite advances in cancer research, cancer incidence and prevalence is growing. Making cancer research infrastructures accessible for all patients, considering the increasing inequalities, requires science policy actions incentivizing research aimed at prevention and cancer therapeutics/care with an increased focus on patients' needs and cost-effective healthcare.

Indexed as

NeoplasmsDelivery of Health CareHumansPrecision MedicineTranslational Research, BiomedicalVatican Citycancer preventioncancer therapeutics/carehealthcareinequalitiesscience policytranslational cancer research

Identifiers

PMID38135904
PMCPMC10850793

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.