Evidence map›Paper›PMID 38135841›Full record

ArticleDysphagia2024

Validation of the DIGEST-FEES as a Global Outcome Measure for Pharyngeal Dysphagia in Parkinson's Disease.

Bendix Labeit, Sriramya Lapa, Paul Muhle, Sonja Suntrup-Krueger, Inga Claus, Florin Gandor, Sigrid Ahring, Stephan Oelenberg, Rainer Dziewas, Tobias Warnecke

Open access · hybridAbstract readValidation Study
In one paragraph

Article in Dysphagia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 16 citations in OpenAlex.

  1. Effects of Puree Type and Color on Ratings of Pharyngeal Residue, Penetration, and Aspiration during FEES: A Prospective Study of 37 Dysphagic Outpatient Adults.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2025
    Trial
  2. Patient-reported swallowing burden and FEES findings in disease-free oropharyngeal cancer survivors after chemoradiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Applicability and reliability of the IDDSI functional diet scale (IDDSI-FDS) in clinical reports of patients with oropharyngeal dysphagia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Observational
  5. Thin Liquid Sip Sizes in Outpatient Adults with Normal and Disordered Swallowing: Modifying Factors and Relationships with Swallowing Safety and Efficiency.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2026
    Article
  6. Article
  7. Respiratory-Swallow Training and Variable Practice in Parkinson's Disease: A Clinical Trial Pilot Study.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Characterizing the Validity of Using VASES to Derive DIGEST-FEES Grades.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2025
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Bendix LabeitDepartment of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. benlabeit@gmail.com.ORCID 0000-0001-6094-3869
Sriramya LapaDepartment of Neurology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Paul MuhleDepartment of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany.
Sonja Suntrup-KruegerDepartment of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany.
Inga ClausDepartment of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany.
Florin GandorMovement Disorders Clinic, Beelitz-Heilstätten, Germany.
Sigrid AhringDepartment of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany.
Stephan OelenbergDepartment of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany.
Rainer DziewasDepartment of Neurology and Neurorehabilitation, Klinikum Osnabrueck - Academic Teaching Hospital of the WWU Muenster, Osnabrueck, Germany.
Tobias WarneckeDepartment of Neurology and Neurorehabilitation, Klinikum Osnabrueck - Academic Teaching Hospital of the WWU Muenster, Osnabrueck, Germany.
University Hospital Münster · DEKlinikum Osnabrück · DEDüsseldorf University Hospital · DEGoethe University Frankfurt · DENeurologisches Fachkrankenhaus für Bewegungsstörungen/Parkinson · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flexible Endoscopic Evaluation of Swallowing (FEES) is one of two diagnostic gold standards for pharyngeal dysphagia in Parkinson's disease (PD), however, validated global outcome measures at the patient level are widely lacking. The Dynamic Imaging Grade of Swallowing Toxicity for Flexible Endoscopic Evaluation of Swallowing (DIGEST-FEES) represents such an outcome measure but has been validated primarily for head and neck cancer collectives. The objective of this study was, therefore, to investigate the validity of the DIGEST-FEES in patients with PD. Content validity was evaluated with a modified Delphi expert survey. Subsequently, 66 FEES videos in PD patients were scored with the DIGEST-FEES. Criterion validity was determined using Spearman's correlation coefficient between the DIGEST-FEES and the Penetration-Aspiration Scale (PAS), the Yale-Residue-Rating-Scale, the Functional-Oral-Intake-Scale (FOIS), and the swallowing-related Unified-Parkinson-Disease-Rating-Scale (UPDRS) items. Inter-rater reliability was determined using 10 randomly selected FEES-videos examined by a second rater. As a result, the overall DIGEST-FEES-rating exhibited significant correlations with the Yale-Valleculae-Residue-Scale (r = 0.84; p < 0.001), the Yale-Pyriform-Sinus-Residue-Scale (r = 0.70; p < 0.001), the FOIS (r =  - 0.55, p < 0.001), and the UPDRS-Swallowing-Item-Score (r = 0.42, p < 0.001). Further, the DIGEST-FEES-safety subscore correlated with the PAS (r = 0.63, p < 0.001). Inter-rater reliability was high for the overall DIGEST-FEES rating (quadratic weighted kappa of 0.82). Therefore, DIGEST-FEES is a valid and reliable score to evaluate overall pharyngeal dysphagia severity in PD. Nevertheless, the modified Delphi survey identified domains where DIGEST-FEES may need to be specifically adapted to PD or neurological collectives in the future.

Indexed as

Deglutition DisordersParkinson DiseaseAgedAged, 80 and overDeglutitionDelphi TechniqueEndoscopyFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePharynxReproducibility of ResultsSeverity of Illness IndexVideo RecordingAspirationDIGESTMalnutritionOropharyngeal dysphagiaParkinsonPneumonia

Identifiers

PMID38135841
PMCPMC11239722
OpenAlexW4390101934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.