SynthesisClinical oral investigations2023
Clinical outcomes of zirconia implants: a systematic review and meta-analysis.
Synthesis in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical behavior of two-piece zirconia implants. A systematic review.Medicina oral, patologia oral y cirugia bucal · 2025Pooled it
- Patient-reported outcomes of zirconia dental implants: a systematic review and future directions.Journal of patient-reported outcomes · 2025Pooled it
- A Randomised Controlled Trial Comparing a One-Piece Zirconia Tissue-Level Implant and Two-Piece Titanium Bone-Level Implant for Maxillary Single Tooth Replacement-3 year Results.Clinical oral implants research · 2026Trial
- One-Year Analysis of Clinical and Radiological Outcomes of Two-Piece Zirconia Compared to Titanium Implants: A Multicenter Prospective Randomized Clinical Trial.Clinical oral implants research · 2026Trial
- A Randomised Controlled Trial Evaluating 3-Year Survival Rates and Technical Complications of Screw-Retained Hybrid Abutment Crowns on Two-Piece Zirconia and Titanium Implants.Clinical oral implants research · 2025Trial
- Effect of Implant Design on Fracture Resistance, Mode, and Crystal Structure of One- and Two-Piece Zirconia Implants With Ceramic or Titanium Abutment Screws: An In Vitro Study.Clinical oral implants research · 2026Article
- Ten-Year Results of a Prospective Case Series on Immediately Provisionalized One-Piece Alumina-Toughened Zirconia (ATZ) Oral Implants for Single-Tooth Restoration and Three-Unit Fixed Dental Prostheses.Journal of clinical periodontology · 2026Article
- Tensile Retention of Lithium Disilicate and Zirconia Crowns Cemented to One-Piece Zirconia Implants: A Pilot In Vitro Study of Cementation Protocol, Resin Cement, and Micro-CT Cement Morphology.Materials (Basel, Switzerland) · 2026Article
- Hydrolytically Stable Organo-Chemical Surface Functionalization of Bioinert High-Performance Ceramics Enables Osseoconduction and Osseointegration In Vivo.Journal of functional biomaterials · 2026Article
- Research Progress and Translational Perspectives of Piezoelectric Materials in Dental Implant Surface Engineering.Journal of functional biomaterials · 2026Review
- Zirconia and Titanium Implants Placed at Two Supracrestal Levels in Fresh Extraction Socket: Canine Periodontitis Model.Clinical implant dentistry and related research · 2026Article
- Clinical outcomes of post-extractive tissue-level implants with transmucosal zirconia collar: a prospective cohort study.Oral and maxillofacial surgery · 2026Article
- Predicting fracture risk in Y-TZP zirconia implants using radiomics-based artificial intelligence.BMC oral health · 2026Article
- Quantifying Stress Shielding in Dental Implants: A Comparative Finite Element Study of Titanium, CFR-PEEK, and Ceramic Materials.Materials (Basel, Switzerland) · 2026Article
- Surface modifications of titanium dental implants: optimizing antibacterial activity and osteoimmunomodulation.Frontiers in bioengineering and biotechnology · 2026Review
- Comparison of Soft and Hard Tissue Outcomes Between Root-Analog Zirconia and Conventional Zirconia Implants: A Prospective Clinical Study.International journal of dentistry · 2026Article
- Clinical evaluation of peri-implantitis relation with implant material.Bioinformation · 2026Article
- Laminin functionalization of zirconia abutments modulates early oral biofilm formation in vitro.Journal of oral microbiology · 2026Article
- Long-Term Performance of Bi-Layered Single Crowns Supported by Zirconia Implants: 7.5-Year Results of a Two-Center Prospective Cohort Study.Clinical oral implants research · 2026Observational
- Ten-Year Results of a Prospective Study on One-Piece Zirconia Oral Implants for Single-Tooth Reconstruction.Clinical oral implants research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the clinical outcomes of zirconia dental implants based on an updated systematic literature review.
methodsAn electronic search was performed in three databases, last updated in June 2023, supplemented by hand searching. The eligibility criteria were clinical studies reporting patients rehabilitated with zirconia implants. The cumulative survival rate (CSR) of implants was calculated. A meta-analysis for marginal bone loss (MBL) under different follow-up times and a meta-regression assessing the relationship between mean MBL and follow-up were done.
resultsTwenty-five studies were included (4017 implants, 2083 patients). Seven studies had follow-up longer than 60 months. 172 implants failed, after a mean of 12.0 ± 16.1 months (min-max 0.3-86.0), of which 47 early failures, and 26 due to implant fracture, the majority in narrow-diameter implants. The 10-year CSR was 95.1%. Implants with coronal part prepared by drills presented statistically significant lower survival than non-prepared implants (p < 0.001). Two-piece implants presented lower survival than one-piece implants (p = 0.017). Implants discontinued from the market presented lower survival than the commercially available ones (p < 0.001). The difference in survival was not significant between implants in maxilla and mandible (p = 0.637). The mean MBL fluctuated between 0.632 and 2.060 mm over long periods of observation (up until 132 months). There was an estimated MBL increase of 0.005 mm per additional month of follow-up.
conclusionZirconia implants present high 10-year CSR and short-term low MBL. The review was registered in PROSPERO (CRD42022342055). CLINICAL RELEVANCE: The clinical outcomes observed for zirconia dental implants are very promising, although these have not yet been extensively studied as titanium alloy implants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.