Evidence map›Paper›PMID 38135502›Full record

ArticleRheumatology (Oxford, England)2025

The incidence and prevalence of juvenile idiopathic arthritis differs between ethnic groups in England.

Richard P Beesley, Kimme L Hyrich, Jenny H Humphreys

Open access · hybridAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 11 citations in OpenAlex.

  1. Differential transcriptional and epigenetic signatures in CD4Journal of translational autoimmunity · 2026
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  13. Community awareness of childhood arthritis in the UK.Rheumatology advances in practice · 2024
    Article
  14. Juvenile idiopathic arthritis and associated uveitis: A review of pathogenesis, diagnosis, and management.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Richard P BeesleyCentre for Epidemiology Versus Arthritis, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.ORCID 0000-0003-1796-4941
Kimme L HyrichCentre for Epidemiology Versus Arthritis, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.ORCID 0000-0001-8242-9262
Jenny H HumphreysCentre for Epidemiology Versus Arthritis, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Manchester Academic Health Science Centre · GB

Funding

Academy of Medical Sciences Starter Grant for Clinical Lecturers SGL020\1047Arthritis Research UK 21755Centre for Epidemiology Versus ArthritisDepartment of Health and Social CareManchester Biomedical Research CentreManchester Biomedical Research Centre NIHR203308NIHR
6 · The paper itself

Abstract

objectivesJIA is a heterogeneous group of rare autoimmune disorders characterized by chronic joint inflammation of unknown aetiology with onset under 16 years. Accurate estimates of disease rates help understand impacts on individuals and society, and provide evidence for health service planning and delivery. This study aimed to produce the first national estimates of incidence and prevalence by ethnic group using electronic health records.

methodsData from the Clinical Practice Research Datalink Aurum, a primary care electronic health record database in England, were used to estimate the incidence and prevalence of JIA by ethnic group amongst children and young people aged under 16 years between 2003 and 2018, with cases validated using Hospital Episode Statistics. χ2 was used to test the difference in proportions compared with the ethnic distribution of England.

resultsA total of 424 incident cases of JIA were identified, 389 validated using Hospital Episode Statistics records. Incidence of JIA was higher amongst those of white ethnic group (6.2 per 100 000 population) compared with mixed (3.0 per 100 000), Asian (2.7 per 100 000) and Black (2.9 per 100 000) communities. The ethnic group distribution of cases differed significantly compared with the general population (P < 0.0001).

conclusionThe incidence and prevalence of JIA differs between ethnic groups, and is different from the general population. This is likely to be due to a combination of genetic and equity factors. Further research to understand the underlying cause of these differences is important to enable targeted interventions and appropriate service provision.

Indexed as

Arthritis, JuvenileEthnicityAdolescentChildChild, PreschoolEnglandFemaleHumansIncidenceInfantMalePrevalenceclinical practice research datalinkequityethnicityincidencejuvenile idiopathic arthritis

Identifiers

PMID38135502
PMCPMC11701319
OpenAlexW4390132028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.