Evidence map›Paper›PMID 38135441›Full record

ArticleThe European respiratory journal2024

CPAP resumption after a first termination and impact on all-cause mortality in France.

Jean-Louis Pépin, Renaud Tamisier, Adam V Benjafield, Pierre Rinder, Florent Lavergne, Anne Josseran, Paul Sinel-Boucher, Peter A Cistulli, Atul Malhotra, Pierre Hornus and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The European respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Jean-Louis PépinUniversity Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, Grenoble, France JPepin@chu-grenoble.fr.ORCID https://orcid.org/0000-0003-3832-2358
Renaud TamisierUniversity Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, Grenoble, France.ORCID https://orcid.org/0000-0003-1128-6529
Adam V BenjafieldResMed Science Center, Sydney, Australia.
Pierre RinderSEMEIA, Paris, France.
Florent LavergneResMed Science Center, Saint Priest, France.ORCID https://orcid.org/0000-0002-8624-5900
Anne JosseranResMed Science Center, Saint Priest, France.
Paul Sinel-BoucherSEMEIA, Paris, France.
Peter A CistulliCharles Perkins Centre, Faculty of Medicine and Health, University Sydney, Sydney, Australia.
Atul MalhotraUniversity of California San Diego, San Diego, CA, USA.
Pierre HornusResMed Science Center, Sydney, Australia.
Sébastien BaillyUniversity Grenoble Alpes, Inserm, CHU Grenoble Alpes, HP2, Grenoble, France.ORCID https://orcid.org/0000-0002-2179-4650
medXcloud group
Inserm · FRResMed (Australia) · AUScience et Médecine (France) · FRSurgiMedia (France) · FRThe University of Sydney · AUUniversity of California San Diego · US

Funding

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's DiseaseR01AG063925 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2020 to 2024
$3.7M
Underlying mechanisms of obesity-induced obstructive sleep apneaR01HL148436 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2020 to 2026
$3.4M
Sleep Apnea Endophenotypes: One Size Does Not Fit AllR01HL154926 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2021 to 2025
$3.3M
The cardiovascular consequences of sleep apnea plus COPD (Overlap syndrome)R01HL166485 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2023 to 2026
$3.1M
VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19R01HL157985 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, NEMATI, SHAMIM · 2022 to 2025
$2.9M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Developing a Diverse Next Generation of Leaders in Respiratory ScienceT32HL166127 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Laura Elise Crotty Alexander, Atul Malhotra · 2023 to 2026
$1.6M
NHLBI NIH HHS R01 HL148436NHLBI NIH HHS R01 HL154926NHLBI NIH HHS R01 HL157985NHLBI NIH HHS R01 HL166485NHLBI NIH HHS T32 HL134632NHLBI NIH HHS T32 HL166127NIA NIH HHS R01 AG063925
6 · The paper itself

Abstract

backgroundContinuation of continuous positive airway pressure (CPAP) therapy after initial prescription has been shown to reduce all-cause mortality

methodsFrench national health insurance reimbursement system data for adults aged ≥18 years were used. CPAP prescription was identified by specific treatment codes. Patients who resumed CPAP after first therapy termination and continued to use CPAP for 1 year were matched with those who resumed CPAP then terminated therapy for a second time.

resultsOut of 103 091 individuals with a first CPAP termination, 26% resumed CPAP over the next 12 months, and 65% of these were still using CPAP 1 year later. Significant predictors of CPAP continuation after resumption included male sex, hypertension and CPAP prescription by a pulmonologist. In the matched population, the risk of all-cause death was 38% lower in individuals who continued using CPAP after therapy resumption

conclusionThese data suggest that individuals with OSA who fail initial therapy with CPAP should be offered a second trial with the device to ensure that effective therapy is not withheld from those who might benefit.

Indexed as

HypertensionSleep Apnea, ObstructiveAdolescentAdultContinuous Positive Airway PressureFranceHumansMalePatient Compliance

Identifiers

PMID38135441
PMCPMC10831141
OpenAlexW4390105589

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.