Evidence map›Paper›PMID 38135024›Full record

ArticleMicrobes and infection

SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophages.

Eric Yau, Linlin Yang, Yan Chen, Todd M Umstead, Anne E Stanley, E Scott Halstead, Chintan K Gandhi, Jonathan W Yewdell, Zissis C Chroneos

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbes and infection. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Eric YauDepartment of Pediatrics, Division of Perinatal-Neonatal Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Linlin YangDepartment of Pediatrics, Division of Perinatal-Neonatal Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Yan ChenDepartment of Pediatrics, Division of Perinatal-Neonatal Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Todd M UmsteadDepartment of Pediatrics, Division of Perinatal-Neonatal Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Anne E StanleyMass Spectrometry Core, Pennsylvania State University College of Medicine, Hershey, PA, USA.
E Scott HalsteadDepartment of Pediatrics, Division of Perinatal-Neonatal Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA; Department of Pediatrics, Division of Pediatric Critical Care Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Chintan K GandhiDepartment of Pediatrics, Division of Perinatal-Neonatal Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Jonathan W YewdellCellular Biology Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
Zissis C ChroneosDepartment of Pediatrics, Division of Perinatal-Neonatal Medicine, Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA, USA; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA, USA. Electronic address: zchroneos@pennstatehealth.psu.edu.
Pennsylvania State University · USNational Institute of Allergy and Infectious Diseases · US

Funding

Regulation of the lung antiviral inflammatory responseR56HL128746 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CHRONEOS, ZISSIS C · 2015 to 2015
$387k
NHLBI NIH HHS R56 HL128746
6 · The paper itself

Abstract

Influenza A virus (IAV) infection causes acute and often lethal inflammation in the lung. The role of macrophages in this adverse inflammation is partially understood. The surfactant protein A receptor 210 (SP-R210) consists of two isoforms, a long (L) SP-R210

Indexed as

Influenza A virusInfluenza, HumanAnimalsHumansInflammationMacrophagesMembrane ProteinsMiceMyosinsProtein IsoformsRNA-Binding ProteinsIFITM3 protein, humanMembrane ProteinsMyosinsProtein IsoformsRNA-Binding ProteinsIFITM3Influenza life-cycleMacrophagesMacropinocytosisMyosin 18A (MYO18A)Surfactant protein A receptor 210 (SP-R210)

Identifiers

PMID38135024
PMCPMC10948314
OpenAlexW4390030255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.