Evidence map›Paper›PMID 38134603›Full record

ArticleMultiple sclerosis and related disorders2024

Initial validation of the university of Alabama Birmingham study of aging life-space assessment in older adults with multiple sclerosis.

Robert W Motl, Frederick W Foley, Mary Ann Picone, Michael L Lipton, Meltem Izzetoglu, Manuel E Hernandez, Roee Holtzer

Open access · greenAbstract read
In one paragraph

Article in Multiple sclerosis and related disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Life space assessment and falls in older adults with multiple sclerosis.Multiple sclerosis and related disorders · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Robert W MotlDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL, United States.
Frederick W FoleyFerkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, United States; Multiple Sclerosis Center, Holy Name Medical Center, Teaneck, NJ, United States.
Mary Ann PiconeMultiple Sclerosis Center, Holy Name Medical Center, Teaneck, NJ, United States.
Michael L LiptonDepartment of Radiology, Columbia University Irving Medical Center, New York, NY, United States; Department of Biomedical Engineering, Columbia University, New York, NY, United States.
Meltem IzzetogluVillanova University, Electrical and Computer Engineering, Villanova, PA, United States.
Manuel E HernandezDepartment of Kinesiology and Community Health, University of Illinois Urbana-Champaign, Urbana, IL, United States; Department of Biomedical and Translational Sciences, Carle Illinois College of Medicine, Urbana, IL, United States.
Roee HoltzerFerkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, United States; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, United States. Electronic address: robmotl@uic.edu.
Holy Name Medical Center · USAlbert Einstein College of Medicine · USColumbia University · USUniversity of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · USVillanova University · US

Funding

Brain Predictors of Mobility and Falls in Older Adults with Multiple SclerosisR01NS109023 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI HOLTZER, ROEE · 2019 to 2023
$3.4M
NINDS NIH HHS R01 NS109023
6 · The paper itself

Abstract

backgroundOlder adults with multiple sclerosis (OAMS) have declines in walking and physical performance that may erode community mobility defined as the spatial extent of mobility in one's daily life and environment.

objectiveThis study provided the first application and validation of the University of Alabama Birmingham Study of Aging Life-Space Assessment (UAB LSA) as a measure of community mobility in OAMS.

methodsThe sample included 97 OAMS and 108 healthy controls (HCs) who completed baseline assessments as part of an ongoing, longitudinal study. The primary assessments included the UAB LSA and timed 25-foot walk (T25FW), short physical performance battery (SPPB), global health score (GHS), and geriatric depression scale (GDS) in both OAMS and HCs, and patient determined disease steps (PDDS) scale in only OAMS.

resultsOAMS had significantly lower UAB LSA scores than HCs (p < .001). UAB LSA scores had strong correlations with T25FW(r

conclusionWe provided initial evidence for UAB LSA scores as a measure of community mobility in OAMS.

Indexed as

Activities of Daily LivingMultiple SclerosisAgedAgingGeriatric AssessmentHumansLongitudinal StudiesCommunity mobilityLife spaceMultiple sclerosisValidationWalking

Identifiers

PMID38134603
PMCPMC10894523
OpenAlexW4389510191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.