Evidence map›Paper›PMID 38134123›Full record

ArticleJournal of chemical information and modeling2024

AIDDISON: Empowering Drug Discovery with AI/ML and CADD Tools in a Secure, Web-Based SaaS Platform.

Andrew Rusinko, Mohammad Rezaei, Lukas Friedrich, Hans-Peter Buchstaller, Daniel Kuhn, Ashwini Ghogare

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Strategies for Identifying Molecules of Interest in Large Chemical Spaces.Journal of chemical information and modeling · 2026
    Article
  2. RiboScreenBiomedicines · 2026
    Review
  3. Article
  4. Review
  5. RiboScreenInternational journal of molecular sciences · 2024
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrew RusinkoMilliporeSigma, 400 Summit Drive, Burlington, Massachusetts 01803, United States.
Mohammad RezaeiMilliporeSigma, 400 Summit Drive, Burlington, Massachusetts 01803, United States.ORCID 0000-0001-5039-2717
Lukas FriedrichMerck Healthcare KGaA, Medicinal Chemistry and Drug Design, Darmstadt 64293, Germany.
Hans-Peter BuchstallerMerck Healthcare KGaA, Medicinal Chemistry and Drug Design, Darmstadt 64293, Germany.ORCID 0000-0002-0577-8319
Daniel KuhnMerck Healthcare KGaA, Medicinal Chemistry and Drug Design, Darmstadt 64293, Germany.
Ashwini GhogareMilliporeSigma, 400 Summit Drive, Burlington, Massachusetts 01803, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread proliferation of artificial intelligence (AI) and machine learning (ML) methods has a profound effect on the drug discovery process. However, many scientists are reluctant to utilize these powerful tools due to the steep learning curve typically associated with them. AIDDISON offers a convenient, secure, web-based platform for drug discovery, addressing the reluctance of scientists to adopt AI and ML methods due to the steep learning curve. By seamlessly integrating generative models, ADMET property predictions, searches in vast chemical spaces, and molecular docking, AIDDISON provides a sophisticated platform for modern drug discovery. It enables less computer-savvy scientists to utilize these powerful tools in their daily activities, as demonstrated by an example of identifying a valuable set of molecules for lead optimization. With AIDDISON, the benefits of AI/ML in drug discovery are accessible to all.

Indexed as

Artificial IntelligenceMachine LearningDrug DiscoveryInternetMolecular Docking SimulationPower, Psychological

Identifiers

PMID38134123
PMCPMC10777390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.