Evidence map›Paper›PMID 38133994›Full record

ArticleJournal of the American Geriatrics Society2024

Migraine headaches are associated with motor vehicle crashes and driving habits among older drivers: Prospective cohort study.

Carolyn G DiGuiseppi, Rachel L Johnson, Marian E Betz, Linda L Hill, David W Eby, Vanya C Jones, Thelma J Mielenz, Lisa J Molnar, David Strogatz, Guohua Li

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. The Effects of Migraine on Driving Safety, Habits, and Risk Perception.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  2. Article
  3. Hallmarks of primary headache: part 1 - migraine.The journal of headache and pain · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Carolyn G DiGuiseppiDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-6440-7817
Rachel L JohnsonDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Marian E BetzDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.
Linda L HillSchool of Public Health, University of California San Diego, La Jolla, California, USA.
David W EbyUniversity of Michigan Transportation Research Institute, Ann Arbor, Michigan, USA.
Vanya C JonesDepartment of Health, Behavior and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Thelma J MielenzCenter for Injury Science and Prevention, Columbia University Irving Medical Center, New York, New York, USA.
Lisa J MolnarUniversity of Michigan Transportation Research Institute, Ann Arbor, Michigan, USA.
David StrogatzBassett Research Institute, Cooperstown, New York, USA.
Guohua LiDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Colorado School of Public Health · USMichigan Department of Transportation · USBassett Medical Center · USColumbia University · USColumbia University Irving Medical Center · USGeriatric Research Education and Clinical Center · USJohns Hopkins University · USUniversity of California San Diego · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
NCATS NIH HHS UL1 TR002535NCATS NIH HHS UM1 TR004399
6 · The paper itself

Abstract

backgroundMigraine headache is common in older adults, often causing symptoms that may affect driving safety. This study examined associations of migraine with motor vehicle crashes (MVCs) and driving habits in older drivers and assessed modification of associations by medication use.

methodsIn a multi-site, prospective cohort study of active drivers aged 65-79 (53% female), we assessed prevalent migraine (i.e., ever had migraine, reported at enrollment), incident migraine (diagnosis first reported at a follow-up visit), and medications typically used for migraine prophylaxis and treatment. During 2-year follow-up, we recorded self-reported MVCs and measured driving habits using in-vehicle GPS devices. Associations of prevalent migraine with driving outcomes were estimated in multivariable mixed models. Using a matched design, associations of incident migraine with MVCs in the subsequent year were estimated with conditional logistic regression. Interactions between migraine and medications were tested in all models.

resultsOf 2589 drivers, 324 (12.5%) reported prevalent migraine and 34 (1.3%) incident migraine. Interactions between migraine and medications were not statistically significant in any models. Prevalent migraine was not associated with MVCs in the subsequent 2 years (adjusted OR [aOR] = 0.98; 95% CI: 0.72, 1.35), whereas incident migraine significantly increased the odds of having an MVC within 1 year (aOR = 3.27; 1.21, 8.82). Prevalent migraine was associated with small reductions in driving days and trips per month and increases in hard braking events in adjusted models.

conclusionOur results suggest substantially increased likelihood of MVCs in the year after newly diagnosed migraine, indicating a potential need for driving safety interventions in these patients. We found little evidence for MVC risk or substantial changes in driving habits associated with prevalent migraine. Future research should examine timing, frequency, and severity of migraine diagnosis and symptoms, and use of medications specifically prescribed for migraine, in relation to driving outcomes.

Indexed as

Automobile DrivingMigraine DisordersAccidents, TrafficAgedFemaleHumansMaleMotor VehiclesProspective Studiesdriving habitsdriving safetymigrainemigraine medicationsmotor vehicle crashes

Identifiers

PMID38133994
PMCPMC11045178
OpenAlexW4390102773

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.