Evidence map›Paper›PMID 38133820›Full record

ArticleACS chemical neuroscience2024

Multitracer Approach to Understanding the Complexity of Reactive Astrogliosis in Alzheimer's Brains.

Igor C Fontana, Amit Kumar, Nobuyuki Okamura, Agneta Nordberg

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Tracing synaptic loss in Alzheimer's brain with SV2A PET-tracer UCB-J.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Igor C FontanaDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, S-141 83 Stockholm, Sweden.
Amit KumarDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, S-141 83 Stockholm, Sweden.ORCID 0000-0001-7669-0712
Nobuyuki OkamuraDepartment of Pharmacology, Tohoku Medical and Pharmaceutical University, Sendai 983-8536, Japan.
Agneta NordbergDivision of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, S-141 83 Stockholm, Sweden.ORCID 0000-0001-7345-5151
Karolinska Institutet · SEKarolinska University Hospital · SETohoku Medical and Pharmaceutical University · JP

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Research Education ComponentP30AG072976 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDREW J SAYKIN · 2021 to 2026
$24.1M
NIA NIH HHS P30 AG010133NIA NIH HHS P30 AG072976
6 · The paper itself

Abstract

A monoamine oxidase B (MAO-B) selective positron emission tomography (PET) tracer [

Indexed as

Alzheimer DiseaseBrainGliosisHumansInflammationMonoamine OxidasePositron-Emission TomographySelegilineMonoamine OxidaseSelegilineAlzheimer’s diseaseastrogliosisBU99008deprenylPET imagingSMBT-1

Identifiers

PMID38133820
PMCPMC10797624
OpenAlexW4390102812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.