Evidence map›Paper›PMID 38133578›Full record

ArticleOrganic letters2024

Modular Synthesis of Benzoylpyridines Exploiting a Reductive Arylation Strategy.

Antonella Ilenia Alfano, Megan Smyth, Scott Wharry, Thomas S Moody, Marcus Baumann

Abstract read
In one paragraph

Article in Organic letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antonella Ilenia AlfanoSchool of Chemistry, University College Dublin, Science Centre South, Dublin 4, Ireland.ORCID 0000-0003-0908-037X
Megan SmythTechnology Department, Almac Sciences, Craigavon BT63 5QD, United Kingdom.ORCID 0000-0002-2771-0382
Scott WharryTechnology Department, Almac Sciences, Craigavon BT63 5QD, United Kingdom.
Thomas S MoodyTechnology Department, Almac Sciences, Craigavon BT63 5QD, United Kingdom.ORCID 0000-0002-8266-0269
Marcus BaumannSchool of Chemistry, University College Dublin, Science Centre South, Dublin 4, Ireland.ORCID 0000-0002-6996-5893

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein we disclose a telescoped flow strategy to access electronically differentiated bisaryl ketones as potentially new and tunable photosensitizers containing both electron-rich benzene systems and electron-deficient pyridyl moieties. Our approach merges a light-driven (365 nm) and catalyst-free reductive arylation between aromatic aldehydes and cyanopyridines with a subsequent oxidation process. The addition of electron-donating and withdrawing substituents on the scaffold allowed effective modification of the absorbance of these compounds in the UV-vis region, while the continuous flow process affords high yields, short residence time, and high throughput.

Identifiers

PMID38133578
PMCPMC11020167

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.