ArticleRadiology. Imaging cancer2024
Whole-Brain Intracellular pH Mapping of Gliomas Using High-Resolution
Open access · diamondAbstract read
In one paragraph
Article in Radiology. Imaging cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 12 citations in OpenAlex.
- Ultra-high-field 7-Tesla MRI in neuro-oncology: a narrative review of current applications and future directions.Quantitative imaging in medicine and surgery · 2026Review
- Integrated analysis of amide proton transfer weighted MRI and proteomics uncovers altered protein dynamics in glioblastoma.Neuroradiology · 2026Article
- Closing the loop on glioblastoma: A roadmap toward developing bioelectronics for continuous monitoring of tumor state.APL bioengineering · 2026Article
- Prediction of MGMT promoter methylation in glioblastoma and grade 4 astrocytoma using fluid-suppressed chemical exchange saturation transfer MRI and machine learning-based segmentation.Frontiers in oncology · 2026Article
- Quantitative MRI Pharmacokinetic Modeling and MALDI Mass Spectrometry Imaging Biodistribution of a pH Mapping MRI Contrast Agent.Theranostics · 2026Article
- Multi-contrast generation and quantitative MRI using a transformer-based framework with RF excitation embeddings.Communications biology · 2025Article
- Multi-site feasibility and reproducibility study on UTE 3D phosphorous MRSI using novel rosette trajectory (PETALUTE).Magnetic resonance in medicine · 2025Article
- Mitochondrial connexin 43 modulates metabolic stress adaptation in glioma cell lines.Cell communication and signaling : CCS · 2025Article
- In vivo imaging of the spatial heterogeneity of intratumoral acidosis (pH) as a marker of the metastatic phenotype in breast cancer.Breast cancer research : BCR · 2025Article
- Toward Noninvasive High-Resolution In Vivo pH Mapping in Brain Tumors byNMR in biomedicine · 2025Article
- Exploring theFrontiers in neuroscience · 2025Article
- Improving standardization and accuracy of in vivo omega plot exchange parameter determination using rotating-frame model-based fitting of quasi-steady-state Z-spectra.Magnetic resonance in medicine · 2025Article
- How to Implement Clinical 7T MRI-Practical Considerations and Experience with Ultra-High-Field MRI.Bioengineering (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 1 institution in 1 country.
Daniel Paech *From the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0001-5755-6833
Nina Weckesser *From the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Vanessa L FrankeFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Johannes BreitlingFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Steffen GörkeFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Katerina Deike-HofmannFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Antje WickFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0003-0020-6386
Moritz SchererFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0003-1203-9351
Andreas UnterbergFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Wolfgang WickFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-6171-634X
Martin BendszusFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Peter BachertFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
Mark E LaddFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-4128-9440
Heinz-Peter SchlemmerFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-9291-0954
Andreas KorzowskiFrom the Divisions of Radiology (D.P., N.W., K.D.H., H.P.S.) and Medical Physics in Radiology (V.L.F., J.B., S.G., P.B., M.E.L., A.K.), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Faculties of Medicine (N.W., M.E.L.) and Physics and Astronomy (V.L.F., P.B., M.E.L.), University of Heidelberg, Heidelberg, Germany; and Departments of Neurology (A.W., W.W.), Neurosurgery (M.S., A.U.), and Neuroradiology (M.B.), Heidelberg University Hospital, Heidelberg, Germany.
German Cancer Research Center · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant tumors commonly exhibit a reversed pH gradient compared with normal tissue, with a more acidic extracellular pH and an alkaline intracellular pH (pH
Indexed as
Brain NeoplasmsGliomaBrainContrast MediaFemaleGadoliniumHumansHydrogen-Ion ConcentrationKi-67 AntigenMagnetic Resonance ImagingMaleMiddle AgedNecrosisProspective StudiesContrast MediaGadoliniumKi-67 Antigen31P MRSI7 TeslaGlioblastomaGliomaImaging BiomarkerpHUltra-High-Field MRI
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.