Evidence map›Paper›PMID 38133265›Full record

ReviewPathogens (Basel, Switzerland)2023

Epidemiology, Molecular Pathogenesis, Immuno-Pathogenesis, Immune Escape Mechanisms and Vaccine Evaluation for HPV-Associated Carcinogenesis.

Meenu Jain, Dhananjay Yadav, Urmila Jarouliya, Vishal Chavda, Arun Kumar Yadav, Bipin Chaurasia, Minseok Song

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  14. Review
  15. Review
  16. Article
  17. Article
  18. CCL20 secreted by KRT15Cell death & disease · 2025
    Article
  19. Review
  20. Human Papillomavirus: An Old New History.Pathogens (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Meenu JainDepartment of Microbiology, Viral Research and Diagnostic Laboratory, Gajra Raja Medical College, Gwalior 474009, Madhya Pradesh, India.
Dhananjay YadavDepartment of Life Science, Yeungnam University, Gyeongsan 38541, Republic of Korea.ORCID 0000-0003-4047-7236
Urmila JarouliyaSOS in Biochemistry, Jiwaji University, Gwalior 474011 Madhya Pradesh, India.
Vishal ChavdaDepartment of Pathology, Stanford School of Medicine, Stanford University Medical Center, Palo Alto, CA 94305, USA.ORCID 0000-0002-5812-3412
Arun Kumar YadavDepartment of Microbiology, Guru Gobind Singh Medical College and Hospital, Baba Farid University of Health Sciences, Faridkot 151203, Punjab, India.
Bipin ChaurasiaDepartment of Neurosurgery, Neurosurgery Clinic, Birgunj 44300, Nepal.ORCID 0000-0002-8392-2072
Minseok SongDepartment of Life Science, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Yeungnam University · KRBir Hospital · NPGajara Raja Medical College · INGuru Gobind Singh Medical College and Hospital · INJiwaji University · INStanford Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV) is implicated in over 90% of cervical cancer cases, with factors like regional variability, HPV genotype, the population studied, HPV vaccination status, and anatomical sample collection location influencing the prevalence and pathology of HPV-induced cancer. HPV-16 and -18 are mainly responsible for the progression of several cancers, including cervix, anus, vagina, penis, vulva, and oropharynx. The oncogenic ability of HPV is not only sufficient for the progression of malignancy, but also for other tumor-generating steps required for the production of invasive cancer, such as coinfection with other viruses, lifestyle factors such as high parity, smoking, tobacco chewing, use of contraceptives for a long time, and immune responses such as stimulation of chronic stromal inflammation and immune deviation in the tumor microenvironment. Viral evasion from immunosurveillance also supports viral persistence, and virus-like particle-based prophylactic vaccines have been licensed, which are effective against high-risk HPV types. In addition, vaccination awareness programs and preventive strategies could help reduce the rate and incidence of HPV infection. In this review, we emphasize HPV infection and its role in cancer progression, molecular and immunopathogenesis, host immune response, immune evasion by HPV, vaccination, and preventive schemes battling HPV infection and HPV-related cancers.

Indexed as

HPV-associated carcinogenesisHPV-infectionimmune evasionimmuno-pathogenesisvaccination

Identifiers

PMID38133265
PMCPMC10745624
OpenAlexW4388946839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.