ReviewVeterinary sciences2023
Estimating Microbial Protein Synthesis in the Rumen-Can 'Omics' Methods Provide New Insights into a Long-Standing Question?
Review in Veterinary sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Ultra-high-performance liquid chromatography high-resolution mass spectrometry-based screening of purine and pyrimidine metabolites in cow milk collected across 4 different seasons.JDS communications · 2026Article
- Composite probiotics improve growth performance and enhance immune and antioxidant capacity in weaned yaks by modulating rumen microbiota and their metabolites.BMC microbiology · 2026Article
- Early supplemental feeding improves post-weaning growth restriction in lambs via the gastrointestinal-metabolic axis.Applied and environmental microbiology · 2026Article
- Reducing Protein Content with and Without Yeast Probiotic Actisaf Sc 47 Supplementation in the Diet of Dairy Cow: Effects on Nitrogen Use, Digestibility, and Rumen Microbial Protein.Animals : an open access journal from MDPI · 2026Article
- Rumen microbiome profiles of dairy cattle are affected by the presence of, and vaccination against, the abomasal parasitic nematode Ostertagia ostertagi.Scientific reports · 2025Article
- Sex-specific microbiota associations with backfat thickness, eye muscle area, and rumen fermentation in Qinchuan cattle.BMC microbiology · 2025Article
- Gut Microbiota of Ruminants and Monogastric Livestock: An Overview.Animals : an open access journal from MDPI · 2025Review
- Comparison of ruminal ecology and blood profiles in Bali, Madura, and Ongole crossbred cattle of Indonesia.Veterinary world · 2025Article
- Relationship between pyrimidines, purines, and fatty acids in milk of dairy cows fed distinct carbohydrate types: A metabolomic approach.JDS communications · 2025Article
- The Effects of Mixed Inoculum Storage Time on In Vitro Rumen Fermentation Characteristics, Microbial Diversity, and Community Composition.Animals : an open access journal from MDPI · 2024Article
- Predicting Microbial Protein Synthesis in Cattle: Evaluation of Extant Equations and Steps Needed to Improve Accuracy and Precision of Future Equations.Animals : an open access journal from MDPI · 2024Review
- Biochemical characterization of a SusD-like protein involved in β-1,3-glucan utilization by an uncultured cow rumenmSphere · 2024Article
- Dose-dependent effect of spent coffee grounds on intake, apparent digestibility, fermentation pattern, methane emissions, microbial protein supply, and antioxidant status in Latxa sheep.Journal of animal science · 2024Article
- A review of genetic resources and trends of omics applications in donkey research: focus on China.Frontiers in veterinary science · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Rumen microbial protein synthesis (MPS) provides at least half of the amino acids for the synthesis of milk and meat protein in ruminants. As such, it is fundamental to global food protein security. Estimating microbial protein is central to diet formulation, maximising nitrogen (N)-use efficiency and reducing N losses to the environment. Whilst factors influencing MPS are well established in vitro, techniques for in vivo estimates, including older techniques with cannulated animals and the more recent technique based on urinary purine derivative (UPD) excretion, are subject to large experimental errors. Consequently, models of MPS used in protein rationing are imprecise, resulting in wasted feed protein and unnecessary N losses to the environment. Newer 'omics' techniques are used to characterise microbial communities, their genes and resultant proteins and metabolites. An analysis of microbial communities and genes has recently been used successfully to model complex rumen-related traits, including feed conversion efficiency and methane emissions. Since microbial proteins are more directly related to microbial genes, we expect a strong relationship between rumen metataxonomics/metagenomics and MPS. The main aims of this review are to gauge the understanding of factors affecting MPS, including the use of the UPD technique, and explore whether omics-focused studies could improve the predictability of MPS, with a focus on beef cattle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.