Evidence map›Paper›PMID 38133213›Full record

ArticleVeterinary sciences2023

Extracutaneous Melanotic Melanoma with Nervous System Involvement in a Buffalo (

José Diomedes Barbosa, Mariana Correia Oliveira, Carlos Magno Chaves Oliveira, Henrique Dos Anjos Bomjardim, Tatiane Teles Albernaz Ferreira, Marcos Dutra Duarte, José Alcides Sarmento da Silveira, Natália da Silva E Silva Silveira, Camila Cordeiro Barbosa, Aluízio Otávio Almeida da Silva and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

José Diomedes BarbosaInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.ORCID 0000-0001-8915-5735
Mariana Correia OliveiraDepartamento de Epidemiologia e Saúde Pública (DESP), Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica 23890-000, RJ, Brazil.
Carlos Magno Chaves OliveiraInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.
Henrique Dos Anjos BomjardimInstituto de Estudos do Trópico Úmido (IETU), Universidade Federal do Sul e Sudeste do Pará (UNIFESSPA), Xinguara 68557-335, PA, Brazil.
Tatiane Teles Albernaz FerreiraInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.
Marcos Dutra DuarteInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.
José Alcides Sarmento da SilveiraInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.
Natália da Silva E Silva SilveiraInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.ORCID 0000-0002-0270-8948
Camila Cordeiro BarbosaInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.ORCID 0000-0001-7837-4246
Aluízio Otávio Almeida da SilvaInstituto de Medicina Veterinária, Universidade Federal do Pará (UFPA), Castanhal 68740-970, PA, Brazil.
Anibal ArmiénCalifornia Animal Health & Food Safety Laboratory System, University of California, Davis, CA 95616, USA.ORCID 0000-0002-1870-9945
Marilene de Farias BritoDepartamento de Epidemiologia e Saúde Pública (DESP), Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica 23890-000, RJ, Brazil.
Universidade Federal do Pará · BRUniversidade Federal Rural do Rio de Janeiro · BRUniversidade Federal do Sul e Sudeste do Pará · BRUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanomas are tumors arising from externally uncontrolled melanocytes that produce varying amounts of melanin. In this study, we report a case of melanoma with neurological impairment without evidence of cutaneous neoplastic lesions in an adult buffalo in the state of Pará, Brazil. Clinically, the buffalo exhibited apathy, decreased mandibular tone, and occasionally an open mouth with motor incoordination, and eventually succumbed to the condition. Necropsy revealed multifocal tumor masses in the brain, pituitary gland, trigeminal ganglion, and spinal cord. The neoplastic cells showed strong positive signals for vimentin, Melan-A, PNL-2, and SOX10. The diagnosis was made via necropsy, histopathology, and positive immunostaining for Melan-A and PNL-2, which are specific markers for melanocyte identification.

Indexed as

buffaloimmunohistochemistryMelan-Aneoplasm

Identifiers

PMID38133213
PMCPMC10747635
OpenAlexW4388849871

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.