Evidence map›Paper›PMID 38132992›Full record

ArticleNanomaterials (Basel, Switzerland)2023

Fixation and Visualization of Full Protein Corona on Lipid Surface of Composite Nanoconstruction.

Anna V Epanchintseva, Julia E Poletaeva, Irina A Bakhno, Vladimir V Belov, Alina E Grigor'eva, Svetlana V Baranova, Elena I Ryabchikova, Ilya S Dovydenko

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna V EpanchintsevaInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.
Julia E PoletaevaInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.
Irina A BakhnoInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.ORCID 0009-0002-8169-9871
Vladimir V BelovInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.
Alina E Grigor'evaInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0001-9853-223X
Svetlana V BaranovaInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0001-9228-3025
Elena I RyabchikovaInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0003-4714-1524
Ilya S DovydenkoInstitute of Chemical Biology and Fundamental Medicine SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0002-6890-4538

Funding

Russian Science Foundation 22-15-00228
6 · The paper itself

Abstract

Spontaneous sorption of proteins on the nanoparticles' surface leads to the fact that nanoparticles in biological media are always enveloped by a layer of proteins-the protein corona. Corona proteins affect the properties of nanoparticles and their behavior in a biological environment. In this regard, knowledge about the composition of the corona is a necessary element for the development of nanomedicine. Because proteins have different sorption efficacy, isolating particles with a full corona and characterizing the full corona is challenging. In this study, we propose a photo-activated cross-linker for full protein corona fixation. We believe that the application of our proposed approach will make it possible to capture and visualize the full corona on nanoparticles coated with a lipid shell.

Indexed as

fixation of full coronafull corona visualizationmultilevel nanoconstructionsphotomodificationprotein coronaserum proteins

Identifiers

PMID38132992
PMCPMC10745710

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.