Evidence map›Paper›PMID 38132949›Full record

ArticleMarine drugs2023

Extending the Structural Diversity of Labdane Diterpenoids from Marine-Derived Fungus

Falei Zhang, Chuanteng Ma, Qian Che, Tianjiao Zhu, Guojian Zhang, Dehai Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Labdane-Type Diterpenoids fromInternational journal of molecular sciences · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Falei ZhangKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0000-0002-0208-8232
Chuanteng MaKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0000-0002-0262-8825
Qian CheKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Tianjiao ZhuKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0000-0003-4185-5593
Guojian ZhangKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0000-0002-4976-8083
Dehai LiKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0000-0002-7191-2002
Ocean University of China · CNQingdao National Laboratory for Marine Science and Technology · CN

Funding

Major Basic Research Programs of Natural Science Foundation of Shandong Province ZR2021ZD28Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology 2022QNLM030003National Natural Science Foundation of China U1906212, 32370061Taishan Scholar Youth Expert Program in Shandong Province 201812021, tsqn 202103153the Fundamental Research Funds for the Central Universities 202172002, 202262015
6 · The paper itself

Abstract

Heterologous biosynthesis has become an effective means to activate fungal silent biosynthetic gene clusters (BGCs) and efficiently utilize fungal genetic resources. Herein, thirteen labdane diterpene derivatives, including five undescribed ones named talarobicins A-E (

Indexed as

Aspergillus nidulansDiterpenesTalaromycesCytochrome P-450 Enzyme SystemMagnetic Resonance SpectroscopyMolecular StructureCytochrome P-450 Enzyme SystemDiterpenesbiosynthesisheterologous expressionlabdane diterpenoidstructural diversityTalaromyces sp. HDN151403

Identifiers

PMID38132949
PMCPMC10744899
OpenAlexW4389286741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.