Evidence map›Paper›PMID 38132921›Full record

ArticleMarine drugs2023

Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma.

Yun Huang, Hongmei Yan, Bingzhi Zhang, Ge Zhu, Jianchen Yu, Xuhan Xiao, Wenxuan He, Yan Chen, Xiaoxia Gao, Zhigang She and 2 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Optimizing CD8Experimental hematology & oncology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yun HuangSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Hongmei YanSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Bingzhi ZhangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Ge ZhuKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou 510080, China.
Jianchen YuKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou 510080, China.
Xuhan XiaoKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou 510080, China.
Wenxuan HeSchool of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yan ChenDepartment of Traditional Chinese Medicine, School of Pharmacy, Anhui Medical University, Hefei 230032, China.
Xiaoxia GaoSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Zhigang SheSchool of Chemistry, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0002-0130-6701
Mengfeng LiSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Jie YuanKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou 510080, China.ORCID 0000-0002-4147-5585
Sun Yat-sen University · CNGuangdong Pharmaceutical University · CN

Funding

Guangdong Marine Economy Development Special Project GDNRC [2022]35Guangdong Marine Economy Development Special Project GDNRC [2023]39Natural Science Foundation of Guangdong Province, China 2022A1515011037
6 · The paper itself

Abstract

Ascomylactam C (AsC) is a new 13-membered-ring macrocyclic alkaloid, which was first isolated and identified in 2019 from the secondary metabolites of the mangrove endophytic fungus

Indexed as

Antineoplastic AgentsLung NeoplasmsMelanomaAnimalsApoptosisCD8-Positive T-LymphocyteseIF-2 KinaseEndoplasmic Reticulum StressImmunogenic Cell DeathMiceMitochondriaTranscription Factor CHOPAntineoplastic AgentseIF-2 KinaseTranscription Factor CHOPascomylactam Cendoplasmic reticulum stressimmunogenic cell deathlung cancermelanomaoxidative stress

Identifiers

PMID38132921
PMCPMC10744434
OpenAlexW4388858960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.