Evidence map›Paper›PMID 38132872›Full record

ReviewMetabolites2023

Modulation of MicroRNAs and Exosomal MicroRNAs after Dietary Interventions for Obesity and Insulin Resistance: A Narrative Review.

Karla G Hernández-Gómez, Azalia Avila-Nava, Luis E González-Salazar, Lilia G Noriega, Aurora E Serralde-Zúñiga, Rocio Guizar-Heredia, Isabel Medina-Vera, Ana Ligia Gutiérrez-Solis, Nimbe Torres, Armando R Tovar and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Karla G Hernández-GómezDepartamento de Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0009-0004-2559-1019
Azalia Avila-NavaHospital Regional de Alta Especialidad de la Península de Yucatán, Mérida 97130, Mexico.
Luis E González-SalazarServicio de Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
Lilia G NoriegaDepartamento de Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0003-2156-9872
Aurora E Serralde-ZúñigaServicio de Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0001-5579-1450
Rocio Guizar-HerediaDepartamento de Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
Isabel Medina-VeraDepartamento de Metodología de la Investigación, Instituto Nacional de Pediatría, Mexico City 04530, Mexico.ORCID 0000-0003-4027-2329
Ana Ligia Gutiérrez-SolisHospital Regional de Alta Especialidad de la Península de Yucatán, Mérida 97130, Mexico.
Nimbe TorresDepartamento de Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-1741-0984
Armando R TovarDepartamento de Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-1292-1312
Martha Guevara-CruzDepartamento de Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-8996-3481
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXHospital Regional de Alta Especialidad del Bajío · MXInstituto Nacional de Pediatria · MX

Funding

Convocatoria 2023 para el fondo de apoyo a proyectos de investigación en el campo de la salud del Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán 2023Hospital Regional de Alta Especialidad de la Península de Yucatán E022
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs approximately 22 nucleotides in length. Their main function is to regulate gene expression at the posttranscriptional level by inhibiting the translation of messenger RNAs (mRNAs). miRNAs originate in the cell nucleus from specific genes, where they can perform their function. However, they can also be found in serum, plasma, or other body fluids travelling within vesicles called exosomes and/or bound to proteins or other particles such as lipoproteins. miRNAs can form complexes outside the cell where they are synthesized, mediating paracrine and endocrine communication between different tissues. In this way, they can modulate the gene expression and function of distal cells. It is known that the expression of miRNAs can be affected by multiple factors, such as the nutritional or pathological state of the individual, or even in conditions such as obesity, insulin resistance, or after any dietary intervention. In this review, we will analyse miRNAs whose expression and circulation are affected in conditions of obesity and insulin resistance, as well as the changes generated after a dietary intervention, with the purpose of identifying new possible biomarkers of early response to nutritional treatment in these conditions.

Indexed as

dietexosomesinsulin resistancemiRNAobesity

Identifiers

PMID38132872
PMCPMC10745452
OpenAlexW4389437901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.