Evidence map›Paper›PMID 38132859›Full record

ArticleMetabolites2023

In Vitro Anti-Oxidant, In Vivo Anti-Hyperglycemic, and Untargeted Metabolomics-Aided-In Silico Screening of Macroalgae Lipophilic Extracts for Anti-Diabetes Mellitus and Anti-COVID-19 Potential Metabolites.

Anggit Listyacahyani Sunarwidhi, Wahyu Rahmaniar, Eka Sunarwidhi Prasedya, Hasriaton Padmi, Sri Widyastuti, Kukuh Waseso Jati Pangestu, Bq Tri Khairina Ilhami, Ervina Handayani, Ni Wayan Putri Utami, Farreh Alan Maulana and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Anggit Listyacahyani SunarwidhiDepartment of Pharmacy, Faculty of Medicine, University of Mataram, Mataram 83115, Indonesia.
Wahyu RahmaniarInstitute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan.
Eka Sunarwidhi PrasedyaBioscience and Biotechnology Research Centre, University of Mataram, Mataram 83115, Indonesia.
Hasriaton PadmiBioscience and Biotechnology Research Centre, University of Mataram, Mataram 83115, Indonesia.
Sri WidyastutiFaculty of Food Technology and Agroindustry, University of Mataram, Mataram 83115, Indonesia.
Kukuh Waseso Jati PangestuBioscience and Biotechnology Research Centre, University of Mataram, Mataram 83115, Indonesia.ORCID 0009-0007-3090-2442
Bq Tri Khairina IlhamiBioscience and Biotechnology Research Centre, University of Mataram, Mataram 83115, Indonesia.ORCID 0000-0003-3555-1964
Ervina HandayaniDepartment of Pharmacy, Faculty of Medicine, University of Mataram, Mataram 83115, Indonesia.
Ni Wayan Putri UtamiDepartment of Pharmacy, Faculty of Medicine, University of Mataram, Mataram 83115, Indonesia.
Farreh Alan MaulanaDepartment of Pharmacy, Faculty of Medicine, University of Mataram, Mataram 83115, Indonesia.
Muhammad Syach Maulad IchfaDepartment of Pharmacy, Faculty of Medicine, University of Mataram, Mataram 83115, Indonesia.
Ari HernawanDepartment of Informatics Engineering, Faculty of Engineering, University of Mataram, Mataram 83115, Indonesia.
University of Mataram · IDTokyo Institute of Technology · JP

Funding

This research was funded by the Indonesian ministry of education, culture, research and technology. 2345/UN18.L1/PP/2023
6 · The paper itself

Abstract

COVID-19 patients with comorbid DM face more severe outcomes, indicating that hyperglycemic conditions exacerbate SARS-CoV-2 infection. Negative side effects from existing hyperglycemia treatments have urged the need for safer compounds. Therefore, sourcing potential compounds from marine resources becomes a new potential approach. Algal lipids are known to possess beneficial activities for human health. However, due to limitations in analyzing large amounts of potential anti-hyperglycemic and anti-COVID-19-related marine metabolites, there is an increasing need for new approaches to reduce risks and costs. Therefore, the main aim of this study was to identify potential compounds in macroalgae

Indexed as

COVID-19diabetes mellituslipophilic compoundsmacroalgaemetabolomics-aided in silico

Identifiers

PMID38132859
PMCPMC10745437
OpenAlexW4389047208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.