Evidence map›Paper›PMID 38132666›Full record

ReviewJournal of cardiovascular development and disease2023

Revolutionizing the Management of Large-Core Ischaemic Strokes: Decoding the Success of Endovascular Therapy in the Recent Stroke Trials.

Gareth Zigui Lim, Jonathan Yexian Lai, Christopher Ying Hao Seet, Carol Huilian Tham, Narayanaswamy Venketasubramanian, Benjamin Yong Qiang Tan, Mingxue Jing, Joshua Yee Peng Yeo, May Zin Myint, Ching-Hui Sia and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Gareth Zigui LimDepartment of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Jonathan Yexian LaiDepartment of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Christopher Ying Hao SeetDepartment of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Carol Huilian ThamDepartment of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Narayanaswamy VenketasubramanianRaffles Neuroscience Centre, Raffles Hospital, Singapore 188770, Singapore.ORCID 0000-0003-3593-6362
Benjamin Yong Qiang TanDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.ORCID 0000-0003-1824-9077
Mingxue JingDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Joshua Yee Peng YeoDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
May Zin MyintDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Ching-Hui SiaYong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.ORCID 0000-0002-2764-2869
Hock Luen TeohDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Vijay Kumar SharmaDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Bernard Poon Lap ChanDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Cunli YangDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Andrew MakmurDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.ORCID 0000-0002-9631-4121
Shao Jin OngDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Leonard Leong Litt YeoDivision of Neurology, Department of Medicine, National University Health System, Singapore 119228, Singapore.ORCID 0000-0002-4249-0402
National University of Singapore · SGNational University Health System · SGTan Tock Seng Hospital · SGRaffles Institution · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endovascular therapy (EVT) has revolutionized the management of acute ischaemic strokes with large vessel occlusion, with emerging evidence suggesting its benefit also in large infarct core volume strokes. In the last two years, four randomised controlled trials have been published on this topic-RESCUE-Japan LIMIT, ANGEL-ASPECT, SELECT2 and TENSION, with overall results showing that EVT improves functional and neurological outcomes compared to medical management alone. This review aims to summarise the recent evidence presented by these four trials and highlight some of the limitations in our current understanding of this topic.

Indexed as

acuteCTendovascular treatmentischaemic strokelarge infarctsMRIradiology

Identifiers

PMID38132666
PMCPMC10743836
OpenAlexW4389883093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.