Evidence map›Paper›PMID 38132309›Full record

ArticleBiology2023

Unraveling the Genomic Association for Milk Production Traits and Signatures of Selection of Cattle in a Harsh Tropical Environment.

Silpa Mullakkalparambil Velayudhan, Tong Yin, Shahin Alam, Kerstin Brügemann, Veerasamy Sejian, Raghavendra Bhatta, Eva Schlecht, Sven König

Abstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Application of GWAS and mGWAS in Livestock and Poultry Breeding.Animals : an open access journal from MDPI · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silpa Mullakkalparambil VelayudhanInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Gießen, Germany.ORCID 0000-0001-8078-4789
Tong YinInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Gießen, Germany.
Shahin AlamAnimal Husbandry in the Tropics and Subtropics, University of Kassel and Georg-August-Universität Göttingen, Steinstr. 19, 37213 Witzenhausen, Germany.
Kerstin BrügemannInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Gießen, Germany.ORCID 0000-0001-7532-8906
Veerasamy SejianNational Institute of Animal Nutrition and Physiology (NIANP), Hosur Rd, Chennakeshava Nagar, Adugodi, Bengaluru 560030, India.ORCID 0000-0002-8224-4521
Raghavendra BhattaNational Institute of Animal Nutrition and Physiology (NIANP), Hosur Rd, Chennakeshava Nagar, Adugodi, Bengaluru 560030, India.ORCID 0000-0001-5074-185X
Eva SchlechtAnimal Husbandry in the Tropics and Subtropics, University of Kassel and Georg-August-Universität Göttingen, Steinstr. 19, 37213 Witzenhausen, Germany.ORCID 0000-0002-5420-2893
Sven KönigInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Gießen, Germany.ORCID 0000-0003-4226-3696

Funding

Deutsche Forschungsgemeinschaft FOR2432/2
6 · The paper itself

Abstract

A study was designed to identify the genomic regions associated with milk production traits in a dairy cattle population reared by smallholder farmers in the harsh and challenging tropical savanna climate of Bengaluru, India. This study is a first-of-its-kind attempt to identify the selection sweeps for the dairy cattle breeds reared in such an environment. Two hundred forty lactating dairy cows reared by 68 farmers across the rural-urban transiting regions of Bengaluru were selected for this study. A genome-wide association study (GWAS) was performed to identify candidate genes for test-day milk yield, solids-not-fat (SNF), milk lactose, milk density and clinical mastitis. Furthermore, the cross-population extended haplotype homozygosity (XP-EHH) methodology was adopted to scan the dairy cattle breeds (Holstein Friesian, Jersey and Crossbred) in Bengaluru. Two SNPs, rs109340659 and rs41571523, were observed to be significantly associated with test-day milk yield. No significant SNPs were observed for the remaining production traits. The GWAS for milk lactose revealed one SNP (rs41634101) that was very close to the threshold limit, though not significant. The potential candidate genes fibrosin-like 1 (

Indexed as

challenging environmentdairy cowsGWASmastitismilk traitsselection signaturethermotolerance

Identifiers

PMID38132309
PMCPMC10740459

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.