Evidence map›Paper›PMID 38132264›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Evolution of Systemic Therapy in Medulloblastoma Including Irradiation-Sparing Approaches.

Naureen Mushtaq, Rahat Ul Ain, Syed Ahmer Hamid, Eric Bouffet

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Surgical resection in medulloblastoma: a crossroads in the molecular era.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  3. Pediatric medulloblastoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Naureen MushtaqDivision of Pediatric Oncology, Department of Oncology, Aga Khan University, Karachi 74800, Pakistan.
Rahat Ul AinDepartment of Pediatric Hematology/Oncology & Bone Marrow Transplant, University of Child Health Sciences, Children's Hospital, Lahore 54600, Pakistan.ORCID 0000-0001-8492-1293
Syed Ahmer HamidDepartment of Pediatric Hematology and Oncology, Indus Hospital & Health Network, Karachi 74800, Pakistan.
Eric BouffetGlobal Neuro-Oncology Program, Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, St. Jude Global, Memphis, TN 38105, USA.ORCID 0000-0002-6832-6539
Aga Khan University · PKIndus Hospital · PKSt. Jude Children's Research Hospital · USUniversity of Health Sciences Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of medulloblastoma in children has dramatically changed over the past four decades, with the development of chemotherapy protocols aiming at improving survival and reducing long-term toxicities of high-dose craniospinal radiotherapy. While the staging and treatment of medulloblastoma were until recently based on the modified Chang's system, recent advances in the molecular biology of medulloblastoma have revolutionized approaches in the management of this increasingly complex disease. The evolution of systemic therapies is described in this review.

Indexed as

chemotherapyhigh-dose chemotherapymedulloblastomasubgrouping

Identifiers

PMID38132264
PMCPMC10743079
OpenAlexW4389923971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.