Evidence map›Paper›PMID 38132263›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Whole Brain and Corpus Callosum Fractional Anisotropy Differences in Patients with Cognitive Impairment.

Kalvis Kaļva, Nauris Zdanovskis, Kristīne Šneidere, Andrejs Kostiks, Guntis Karelis, Ardis Platkājis, Ainārs Stepens

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. From Stress to Synapse: The Neuronal Atrophy Pathway to Mood Dysregulation.International journal of molecular sciences · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kalvis KaļvaDepartment of Radiology, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0001-6155-7556
Nauris ZdanovskisDepartment of Radiology, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0002-8255-7392
Kristīne ŠneidereMilitary Medicine Research and Study Centre, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0002-4392-9392
Andrejs KostiksDepartment of Neurology and Neurosurgery, Riga East University Hospital, LV-1038 Riga, Latvia.ORCID 0000-0002-1389-1944
Guntis KarelisDepartment of Neurology and Neurosurgery, Riga East University Hospital, LV-1038 Riga, Latvia.ORCID 0000-0002-9586-2775
Ardis PlatkājisDepartment of Radiology, Riga Stradins University, LV-1007 Riga, Latvia.
Ainārs StepensMilitary Medicine Research and Study Centre, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0002-6621-0196

Funding

Riga Stradiņš University Alumni Association Student research and innovation grants 1-6.2.2/1."Support for involving students in scientific research" at Rīga Stradiņš University and with financing from the European Social Fund and Latvian state budget 8.2.2.0/20/I/004
6 · The paper itself

Abstract

Diffusion tensor imaging (DTI) is an MRI analysis method that could help assess cognitive impairment (CI) in the ageing population more accurately. In this research, we evaluated fractional anisotropy (FA) of whole brain (WB) and corpus callosum (CC) in patients with normal cognition (NC), mild cognitive impairment (MCI), and moderate/severe cognitive impairment (SCI). In total, 41 participants were included in a cross-sectional study and divided into groups based on Montreal Cognitive Assessment (MoCA) scores (NC group, nine participants, MCI group, sixteen participants, and SCI group, sixteen participants). All participants underwent an MRI examination that included a DTI sequence. FA values between the groups were assessed by analysing FA value and age normative percentile. We did not find statistically significant differences between the groups when analysing CC FA values. Both approaches showed statistically significant differences in WB FA values between the MCI-SCI and MCI-NC groups, where the MCI group participants showed the highest mean FA and highest mean FA normative percentile results in WB.

Indexed as

cognitioncognitive impairmentdementiadiffusion tensor imagingfractional anisotropymild cognitive impairmentMontreal Cognitive Assessmentneuroradiology

Identifiers

PMID38132263
PMCPMC10742911

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.