Evidence map›Paper›PMID 38132257›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Advancing Colorectal Cancer Diagnosis with AI-Powered Breathomics: Navigating Challenges and Future Directions.

Ioannis K Gallos, Dimitrios Tryfonopoulos, Gidi Shani, Angelos Amditis, Hossam Haick, Dimitra D Dionysiou

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ioannis K GallosInstitute of Communication and Computer Systems, National Technical University of Athens, Zografos Campus, 15780 Athens, Greece.ORCID 0000-0001-5172-5587
Dimitrios TryfonopoulosInstitute of Communication and Computer Systems, National Technical University of Athens, Zografos Campus, 15780 Athens, Greece.
Gidi ShaniLaboratory for Nanomaterial-Based Devices, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
Angelos AmditisInstitute of Communication and Computer Systems, National Technical University of Athens, Zografos Campus, 15780 Athens, Greece.ORCID 0000-0002-4089-1990
Hossam HaickLaboratory for Nanomaterial-Based Devices, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
Dimitra D DionysiouInstitute of Communication and Computer Systems, National Technical University of Athens, Zografos Campus, 15780 Athens, Greece.
National Technical University of Athens · GRTechnion – Israel Institute of Technology · IL

Funding

European Union's Horizon Europe research and innovation programme 101097036 (ONCOSCREEN)
6 · The paper itself

Abstract

Early detection of colorectal cancer is crucial for improving outcomes and reducing mortality. While there is strong evidence of effectiveness, currently adopted screening methods present several shortcomings which negatively impact the detection of early stage carcinogenesis, including low uptake due to patient discomfort. As a result, developing novel, non-invasive alternatives is an important research priority. Recent advancements in the field of breathomics, the study of breath composition and analysis, have paved the way for new avenues for non-invasive cancer detection and effective monitoring. Harnessing the utility of Volatile Organic Compounds in exhaled breath, breathomics has the potential to disrupt colorectal cancer screening practices. Our goal is to outline key research efforts in this area focusing on machine learning methods used for the analysis of breathomics data, highlight challenges involved in artificial intelligence application in this context, and suggest possible future directions which are currently considered within the framework of the European project ONCOSCREEN.

Indexed as

artificial intelligenceautomated diagnosisbreathomicscolorectal cancermachine learningmanifold learningONCOSCREENvalidationvolatile organic compounds

Identifiers

PMID38132257
PMCPMC10743128
OpenAlexW4389784658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.