Evidence map›Paper›PMID 38132192›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Landscape of Innovative Methods for Early Diagnosis of Gastric Cancer: A Systematic Review.

Alexandra Orășeanu, Mihaela Cristina Brisc, Octavian Adrian Maghiar, Horia Popa, Ciprian Mihai Brisc, Sabina Florina Șolea, Teodor Andrei Maghiar, Ciprian Brisc

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Oral vitamin B₁₂ after total gastrectomy for gastric cancer: mapping the evidence.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Review
  2. Article
  3. Targeted metabolomic profiling of gastric cancer biopsies.The Indian journal of medical research · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Current and emerging approaches to manage chronic inflammatory gut disorders.Frontiers in cellular and infection microbiology · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Biological Activity of Natural and Synthetic Peptides as Anticancer Agents.International journal of molecular sciences · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra OrășeanuClinic of Gastroenterology, Bihor Clinical County Emergency Hospital, 410169 Oradea, Romania.
Mihaela Cristina BriscFaculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania.ORCID 0000-0003-3603-8070
Octavian Adrian MaghiarDoctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.
Horia PopaClinical Emergency Hospital "Prof. Dr. Agrippa Ionescu", 011356 Bucharest, Romania.
Ciprian Mihai BriscFaculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania.
Sabina Florina ȘoleaClinic of Gastroenterology, Bihor Clinical County Emergency Hospital, 410169 Oradea, Romania.
Teodor Andrei MaghiarDoctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.
Ciprian BriscDoctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.ORCID 0000-0003-4416-2848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From a global perspective, gastric cancer (GC) persists as a significant healthcare issue. In the Western world, the majority of cases are discovered at late stages, when the treatment is generally unsuccessful. There are no organized screening programs outside of Asia (Japan and Republic of Korea). Traditional diagnosis techniques (such as upper endoscopy), conventional tumor markers (CEA, CA19-9, and CA72-4), radiographic imaging, and CT scanning all have drawbacks. The gold standard for the earliest detection of cancer and related premalignant lesions is still endoscopy with a proper biopsy follow-up. Since there are currently no clinically approved biomarkers for the early diagnosis of GC, the identification of non-invasive biomarkers is expected to help improve the prognosis and survival rate of these patients. The search for new screening biomarkers is currently underway. These include genetic biomarkers, such as circulating tumor cells, microRNAs, and exosomes, as well as metabolic biomarkers obtained from biofluids. Meanwhile, cutting-edge high-resolution endoscopic technologies are demonstrating promising outcomes in the visual diagnosis of mucosal lesions with the aid of linked color imaging and machine learning models. Following the PRISMA guidelines, this study examined the articles in databases such as PubMed, resulting in 167 included articles. This review discusses the currently available and emerging methods for diagnosing GC early on, as well as new developments in the endoscopic detection of early lesions of the stomach.

Indexed as

biomarkersendoscopygastric cancergastroenterologymetabolomicsscreening

Identifiers

PMID38132192
PMCPMC10742893

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.