Evidence map›Paper›PMID 38132141›Full record

ReviewCells2023

Beyond the Basics: Unraveling the Complexity of Coronary Artery Calcification.

Satwat Hashmi, Pashmina Wiqar Shah, Zouhair Aherrahrou, Elena Aikawa, Rédouane Aherrahrou

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Proteogenomic Analysis of Coronary Artery Calcification in Human Populations.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Satwat HashmiDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.
Pashmina Wiqar ShahInstitute for Cardiogenetics, Universität zu Lübeck, 23562 Lübeck, Germany.
Zouhair AherrahrouInstitute for Cardiogenetics, Universität zu Lübeck, 23562 Lübeck, Germany.
Elena AikawaCardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Rédouane AherrahrouInstitute for Cardiogenetics, Universität zu Lübeck, 23562 Lübeck, Germany.ORCID 0000-0001-8148-9554
Universität Hamburg · DEAga Khan University · PKBrigham and Women's Hospital · US

Funding

American Heart Association Postdoctoral Fellowship 18POST33990046, the University of Eastern Finland (Researcher Fellowship), the Finnish Foundation for Cardiovascular Research, German Centre for Cardiovascular Research (DZHK), the Junior Investigator Awa S0199/10097/2023
6 · The paper itself

Abstract

Coronary artery calcification (CAC) is mainly associated with coronary atherosclerosis, which is an indicator of coronary artery disease (CAD). CAC refers to the accumulation of calcium phosphate deposits, classified as micro- or macrocalcifications, that lead to the hardening and narrowing of the coronary arteries. CAC is a strong predictor of future cardiovascular events, such as myocardial infarction and sudden death. Our narrative review focuses on the pathophysiology of CAC, exploring its link to plaque vulnerability, genetic factors, and how race and sex can affect the condition. We also examined the connection between the gut microbiome and CAC, and the impact of genetic variants on the cellular processes involved in vascular calcification and atherogenesis. We aimed to thoroughly analyze the existing literature to improve our understanding of CAC and its potential clinical and therapeutic implications.

Indexed as

AtherosclerosisCoronary Artery DiseaseMyocardial InfarctionPlaque, AtheroscleroticHumansatherosclerosiscoronary artery calcificationcoronary artery diseasegeneticsgenome-wide association studies

Identifiers

PMID38132141
PMCPMC10742130
OpenAlexW4389616787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.