Evidence map›Paper›PMID 38132127›Full record

ArticleCells2023

The Identification of Nuclear FMRP Isoform Iso6 Partners.

Nassim Ledoux, Emeline I J Lelong, Alexandre Simard, Samer Hussein, Pauline Adjibade, Jean-Philippe Lambert, Rachid Mazroui

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nassim LedouxCentre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Emeline I J LelongCentre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.ORCID 0000-0002-9408-1694
Alexandre SimardCentre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Samer HusseinCentre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Pauline AdjibadeCentre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Jean-Philippe LambertCentre de Recherche du CHU de Québec-Université Laval, Axe Endocrinologie et néphrologie, Département de Médecine Moléculaire, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.ORCID 0000-0002-0833-1221
Rachid MazrouiCentre de Recherche du CHU de Québec-Université Laval, Axe Oncologie, Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada.
Université Laval · CAPROTEO · CA

Funding

Cancer Research Society 839081 FO-FO131961Natural Sciences and Engineering Research Council MOP-CG095386
6 · The paper itself

Abstract

A deficiency of FMRP, a canonical RNA-binding protein, causes the development of Fragile X Syndrome (FXS), which is characterised by multiple phenotypes, including neurodevelopmental disorders, intellectual disability, and autism. Due to the alternative splicing of the encoding

Indexed as

Fragile X Messenger Ribonucleoprotein 1Proteasome Endopeptidase ComplexAlternative SplicingDNAProtein IsoformsDNAFragile X Messenger Ribonucleoprotein 1Proteasome Endopeptidase ComplexProtein IsoformsFMRPGFP-Trapmass spectrometryproteasomeRNA-binding proteins

Identifiers

PMID38132127
PMCPMC10742089
OpenAlexW4389564064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.