Evidence map›Paper›PMID 38132102›Full record

ArticleCells2023

Abstinence Restores Cardiac Function in Mice with Established Alcohol-Induced Cardiomyopathy.

Joshua M Edavettal, Nicholas R Harris, Sarah E Cohen, Janos Paloczi, Bysani Chandrasekar, Jason D Gardner

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joshua M EdavettalDepartment of Physiology, LSU Health Sciences Center-New Orleans, New Orleans, LA 70112, USA.
Nicholas R HarrisDepartment of Physiology, LSU Health Sciences Center-New Orleans, New Orleans, LA 70112, USA.
Sarah E CohenDepartment of Physiology, LSU Health Sciences Center-New Orleans, New Orleans, LA 70112, USA.
Janos PalocziDepartment of Physiology, LSU Health Sciences Center-New Orleans, New Orleans, LA 70112, USA.ORCID 0000-0002-7691-4138
Bysani ChandrasekarDepartment of Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA.
Jason D GardnerDepartment of Physiology, LSU Health Sciences Center-New Orleans, New Orleans, LA 70112, USA.
Louisiana State University Health Sciences Center New Orleans · USHarry S. Truman Memorial Veterans' Hospital · US

Funding

Role of novel RNA binding protein LARP6 in alcoholic cardiomyopathyR21AA029747 · NIAAA · LSU HEALTH SCIENCES CENTER · PI BYSANI, CHANDRASEKAR, GARDNER, JASON DAVIN · 2023 to 2024
$413k
Larp6 and Alcoholic CardiomyopathyF30AA030472 · NIAAA · LSU HEALTH SCIENCES CENTER · PI Joshua Edavettal · 2022 to 2026
$268k
BLRD VA I01 BX005845BLRD VA IK6 BX004016NIAAA NIH HHS F30 AA030472NIAAA NIH HHS R21 AA029747NIH HHS F30AA030472NIH HHS R21AA029747
6 · The paper itself

Abstract

Alcohol-induced cardiomyopathy (ACM) has a poor prognosis with up to a 50% chance of death within four years of diagnosis. There are limited studies investigating the potential of abstinence for promoting repair after alcohol-induced cardiac damage, particularly in a controlled preclinical study design. Here, we developed an exposure protocol that led to significant decreases in cardiac function in C57BL6/J mice within 30 days; dP/dt max decreased in the mice fed alcohol for 30 days (8054 ± 664.5 mmHg/s compared to control mice: 11,188 ± 724.2 mmHg/s,

Indexed as

CardiomyopathiesHeartAnimalsBiomarkersBlood PressureEthanolMiceBiomarkersEthanolabstinencealcohol-induced cardiomyopathycardiac functionreversal

Identifiers

PMID38132102
PMCPMC10742080
OpenAlexW4389442936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.