Evidence map›Paper›PMID 38132095›Full record

ArticleCells2023

Reprogramming Megakaryocytes for Controlled Release of Platelet-like Particles Carrying a Single-Chain Thromboxane A

Renzhong Lu, Yan Li, Anna Xu, Bridgette King, Ke-He Ruan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Engineering platelets as cancer therapeutics.Nature reviews. Clinical oncology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Renzhong LuThe Center for Experimental Therapeutics and Pharmacoinformatics, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Yan LiThe Center for Experimental Therapeutics and Pharmacoinformatics, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Anna XuThe Center for Experimental Therapeutics and Pharmacoinformatics, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Bridgette KingThe Center for Experimental Therapeutics and Pharmacoinformatics, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Ke-He RuanThe Center for Experimental Therapeutics and Pharmacoinformatics, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204, USA.

Funding

Prostaglandin I synthase, Thromboxane A synthase & Prostaglandin E synthaseR01HL056712 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RUAN, KE-HE · 2000 to 2009
$2.3M
STRUCTURE &FUNCTION RELATIONSHIP: PROSTANOID RECEPTORSR01HL079389 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RUAN, KE-HE · 2005 to 2008
$1.4M
NHLBI NIH HHS R01 HL056712NHLBI NIH HHS R01 HL079389NIH HHS RO1 HL56712
6 · The paper itself

Abstract

In this study, we reported that novel single-chain fusion proteins linking thromboxane A

Indexed as

MegakaryocytesThromboxanesBlood PlateletsDelayed-Action PreparationsGTP-Binding ProteinsHumansThromboxane A2Delayed-Action PreparationsGTP-Binding ProteinsThromboxane A2ThromboxanesG-protein-coupled receptormegakaryocyteplatelet-linked particles

Identifiers

PMID38132095
PMCPMC10741393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.