Evidence map›Paper›PMID 38132094›Full record

ArticleCells2023

Levels of Cell-Free DNA in Kidney Failure Patients before and after Renal Transplantation.

Chiara Leotta, Leah Hernandez, Lubomira Tothova, Samsul Arefin, Paola Ciceri, Mario Gennaro Cozzolino, Peter Barany, Milan Chromek, Peter Stenvinkel, Karolina Kublickiene

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Chiara LeottaDivision of Renal Medicine, Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, 17177 Stockholm, Sweden.
Leah HernandezDivision of Renal Medicine, Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0002-7443-1626
Lubomira TothovaInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, 81108 Bratislava, Slovakia.ORCID 0000-0001-9162-4916
Samsul ArefinDivision of Renal Medicine, Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0002-8050-9100
Paola CiceriRenal Division, Department of Health Sciences, ASST Santi Paolo e Carlo Hospital Milan, University of Milan, 20142 Milan, Italy.
Mario Gennaro CozzolinoRenal Division, Department of Health Sciences, ASST Santi Paolo e Carlo Hospital Milan, University of Milan, 20142 Milan, Italy.ORCID 0000-0002-8494-6252
Peter BaranyDivision of Renal Medicine, Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, 17177 Stockholm, Sweden.
Milan ChromekDivision of Renal Medicine, Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0002-8941-057X
Peter StenvinkelDivision of Renal Medicine, Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0002-8785-4820
Karolina KublickieneDivision of Renal Medicine, Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0002-4841-6836
Karolinska Institutet · SEUniversity of Milan · ITComenius University Bratislava · SKKarolinska University Hospital · SE

Funding

CIMED, Heart and Lung Foundation 20160384GOING-FWD Consortium Vetenskapsrådet 2018-00932 GOING-FWD
6 · The paper itself

Abstract

Circulating cell-free DNA (cfDNA) has diverse applications in oncological, prenatal, toxicological, cardiovascular, and autoimmune diseases, diagnostics, and organ transplantation. In particular, mitochondrial cfDNA (mt-cfDNA) is associated with inflammation and linked to early vascular ageing (EVA) in end-stage kidney failure (ESKF), which could be a noninvasive marker for graft rejection and organ damage. Plasma samples from 44 ESKF patients, of whom half (

Indexed as

Cell-Free Nucleic AcidsKidney Failure, ChronicKidney TransplantationFibrosisHumansMaleRenal DialysisCell-Free Nucleic Acidscell-free DNAend-stage kidney failurehemodialysiskidney transplantationsex difference

Identifiers

PMID38132094
PMCPMC10741614
OpenAlexW4389391648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.