Evidence map›Paper›PMID 38131928›Full record

ArticleGels (Basel, Switzerland)2023

Toxicological Profile and Anti-Inflammatory Effect of Mucoadhesive Gel from Residues of

Júlia Amanda Rodrigues Fracasso, Ingrid Yuri Galindo Sikina, Luísa Taynara Silvério da Costa, Lucas Pires Guarnier, João Tadeu Ribeiro-Paes, Fernando Yutaka de Ferreira, Luan Victor Coelho de Almeida, Beatriz de Castro Silva, Débora de Barros Barbosa, Valdecir Farias Ximenes and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Júlia Amanda Rodrigues FracassoSchool of Dentistry, São Paulo State University (UNESP), 1193, José Bonifacio Street, Araçatuba 16015-050, Brazil.
Ingrid Yuri Galindo SikinaDepartment of Biotechnology, School of Sciences and Languages, São Paulo State University (UNESP), 2100, Dom Antonio Avenue, Assis 19806-900, Brazil.
Luísa Taynara Silvério da CostaSchool of Dentistry, São Paulo State University (UNESP), 1193, José Bonifacio Street, Araçatuba 16015-050, Brazil.
Lucas Pires GuarnierDepartment of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14048-900, Brazil.
João Tadeu Ribeiro-PaesDepartment of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14048-900, Brazil.
Fernando Yutaka de FerreiraDepartment of Biotechnology, School of Sciences and Languages, São Paulo State University (UNESP), 2100, Dom Antonio Avenue, Assis 19806-900, Brazil.
Luan Victor Coelho de AlmeidaSchool of Dentistry, São Paulo State University (UNESP), 1193, José Bonifacio Street, Araçatuba 16015-050, Brazil.
Beatriz de Castro SilvaSchool of Dentistry, São Paulo State University (UNESP), 1193, José Bonifacio Street, Araçatuba 16015-050, Brazil.
Débora de Barros BarbosaSchool of Dentistry, São Paulo State University (UNESP), 1193, José Bonifacio Street, Araçatuba 16015-050, Brazil.ORCID 0000-0002-3623-5093
Valdecir Farias XimenesDepartment of Chemistry, Faculty of Sciences, São Paulo State University (UNESP), Bauru 17033-360, Brazil.
Desirre VenkliDepartment of Biochemistry and Chemical Technology, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, Brazil.ORCID 0000-0003-3291-1979
Amanda Martins VielSão Camilo University Center, São Paulo 04263-200, Brazil.
Lucinéia Dos SantosSchool of Dentistry, São Paulo State University (UNESP), 1193, José Bonifacio Street, Araçatuba 16015-050, Brazil.
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BRCentro Universitário Nossa Senhora do Patrocínio · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

Inflammation is a natural protective reaction of the body against endogenous and exogenous damage, such as tissue injuries, trauma, and infections. Thus, when the response is adequate, inflammation becomes a defense mechanism to repair damaged tissue, whereas when the response is inadequate and persistent, the increase in inflammatory cells, cytosines, and chymosins impair tissue regeneration and promote a response harmful to the organism. One example is chronic tissue inflammation, in which a simple lesion can progress to ulcers and even necrosis. In this situation, the anti-inflammatory medications available in therapy are not always effective. For this reason, the search for new treatments, developed from medicinal plants, has increased. In this direction, the plants

Indexed as

herbalinflammationsaponins

Identifiers

PMID38131928
PMCPMC10743268
OpenAlexW4389189873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.