Evidence map›Paper›PMID 38131910›Full record

ArticleGels (Basel, Switzerland)2023

Cysteine-Silver-Polymer Systems for the Preparation of Hydrogels and Films with Potential Applications in Regenerative Medicine.

Dmitry V Vishnevetskii, Arif R Mekhtiev, Dmitry V Averkin, Elizaveta E Polyakova

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Dmitry V VishnevetskiiDepartment of Physical Chemistry, Tver State University, Building 33, Zhelyabova Str., Tver 170100, Russia.ORCID 0000-0003-1382-9451
Arif R MekhtievInstitute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Str., Moscow 191121, Russia.
Dmitry V AverkinRussian Metrological Institute of Technical Physics and Radio Engineering, Worker's Settlement Mendeleevo, Building 11, Moscow 141570, Russia.
Elizaveta E PolyakovaDepartment of Physical Chemistry, Tver State University, Building 33, Zhelyabova Str., Tver 170100, Russia.
Tver State University · RUAll-Russian Scientific Research Institute of Physical-Technical and Radiotechnical Measurements · RUInstitute of Biomedical Chemistry · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2022-305
6 · The paper itself

Abstract

Herein, the problem concerning the poorer mechanical properties of gels based on low molecular weight gelators (LMWGs)-L-cysteine and silver nitrate-was solved by the addition of various polymers-polyvinyl alcohol (PVA), polyvinyl pyrrolidone (PVP) and polyethylene glycol (PEG)-to the initial cysteine-silver sol (CSS). The physicochemical methods of analysis-viscosimetry, UV spectroscopy, DLS, and SEM-identified that cysteine-silver hydrogels (CSG) based on PVA possess the best rheological properties and porous microstructure (the average pore size is 2-10 µm) compared to gels without the polymer or with PVP or PEG. Such gels are able to form cysteine-silver cryogels (CSC) and then porous cysteine-silver films (CSF) with an average pore size of 10-20 µm and good mechanical, swelling, and adhesion to skin characteristics as long as the structure of CSS particles remains stable. In vitro experiments have shown that hydrogels are non-toxic to normal human fibroblast cells. The obtained materials could potentially be applied to regenerative medicine.

Indexed as

biocompatible polymerscytotoxicityhydrogelsL-cysteinemicrostructureporous filmsself-assemblysilver nanoparticles

Identifiers

PMID38131910
PMCPMC10742544
OpenAlexW4388944177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.