Evidence map›Paper›PMID 38131076›Full record

ArticleChemical science2023

Unveiling autophagy and aging through time-resolved imaging of lysosomal polarity with a delayed fluorescent emitter.

Subhadeep Das, Abhilasha Batra, Subhankar Kundu, Rati Sharma, Abhijit Patra

Open access · diamondAbstract read
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Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Subhadeep DasDepartment of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal Bhopal Madhya Pradesh 462066 India abhijit@iiserb.ac.in.ORCID https://orcid.org/0000-0002-3588-3726
Abhilasha BatraDepartment of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal Bhopal Madhya Pradesh 462066 India abhijit@iiserb.ac.in.ORCID https://orcid.org/0000-0001-8599-4777
Subhankar KunduDepartment of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal Bhopal Madhya Pradesh 462066 India abhijit@iiserb.ac.in.ORCID https://orcid.org/0000-0001-9294-5551
Rati SharmaDepartment of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal Bhopal Madhya Pradesh 462066 India abhijit@iiserb.ac.in.ORCID https://orcid.org/0000-0003-1444-5708
Abhijit PatraDepartment of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal Bhopal Madhya Pradesh 462066 India abhijit@iiserb.ac.in.ORCID https://orcid.org/0000-0003-3144-1813
Indian Institute of Science Education and Research, Bhopal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detecting the lysosomal microenvironmental changes like viscosity, pH, and polarity during their dynamic interorganelle interactions remains an intriguing area that facilitates the elucidation of cellular homeostasis. The subtle variation of physiological conditions can be assessed by deciphering the lysosomal microenvironments during lysosome-organelle interactions, closely related to autophagic pathways leading to various cellular disorders. Herein, we shed light on the dynamic lysosomal polarity in live cells and a multicellular model organism,

Identifiers

PMID38131076
PMCPMC10732132
OpenAlexW4388630522

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.