Evidence map›Paper›PMID 38131002›Full record

ArticleInfluenza and other respiratory viruses2023

Comparison of the clinical features and outcomes of severe seasonal influenza and COVID-19 patients in Tunisia between 2021 and 2022.

Jalila Ben Khelil, Rihab Yazidi, Nacef Ben Mrad, Fatma Jarraya, Emna Rachdi, Samia Ayed, Amira Jamoussi, Afif Ben Salah, Mohamed Besbes

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jalila Ben KhelilIntensive Care Department Abderrahman Mami Hospital Ariana Tunisia.ORCID 0000-0003-3557-0559
Rihab YazidiService of Medical Epidemiology Institut Pasteur de Tunis Tunis-Belvédère Tunisia.
Nacef Ben MradIntensive Care Department Abderrahman Mami Hospital Ariana Tunisia.
Fatma JarrayaIntensive Care Department Abderrahman Mami Hospital Ariana Tunisia.
Emna RachdiIntensive Care Department Abderrahman Mami Hospital Ariana Tunisia.
Samia AyedIntensive Care Department Abderrahman Mami Hospital Ariana Tunisia.
Amira JamoussiIntensive Care Department Abderrahman Mami Hospital Ariana Tunisia.
Afif Ben SalahLaboratory of Transmission, Control and Immunobiology of Infections (LR16IPT02); Institut Pasteur de Tunis Tunis-Belvédère Tunisia.
Mohamed BesbesIntensive Care Department Abderrahman Mami Hospital Ariana Tunisia.
Tunis University · TNInstitut Pasteur de Tunis · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We compared patients diagnosed at a SARI (severe acute respiratory infections) surveillance site with COVID-19 and those with seasonal influenza to investigate the clinical differences, common features, and outcomes. Methods: We conducted a descriptive, retrospective study in the Medical Intensive Care Unit (ICU) at Abderrahman Mami Hospital between September 2021 and April 2022. Demographic, clinical, and biological data as well as outcomes were recorded for all patients. Results: Among 223 SARI patients, 83 were confirmed COVID-19, and 22 were influenza positive. The distribution according to gender was similar; but patients with influenza were younger than those suffering from COVID-19(mean age 60.36 SD 17.28 vs. 61.88 SD 17.91; P = 0.601). In terms of underlying chronic diseases, the frequency was 84.3% in the COVID-19 group and 72.7% in the influenza group. COVID-19 patients had a longer duration of hospitalization (mean [SD], 9.51 days [8.47 days] vs. 7.33 days [8.82 days]; P = 0.003), and a more frequent need for invasive ventilation (80 [97.4%] vs. 20 [92.3]). Case fatality was also higher among this group compared to the latter (39 [47%] vs. 6 [27.3%], P = 0.01). Conclusion: This exploratory study suggests higher severity of COVID-19 compared to seasonal influenza among SARI hospitalized patients even during the Omicron wave. Further research on higher sample sizes is required to confirm this conclusion.

Indexed as

COVID-19Influenza, HumanHospitalizationHumansMiddle AgedRetrospective StudiesSeasonsTunisiacomparisonCOVID‐19influenzamanagementmortalityoutcomes

Identifiers

PMID38131002
PMCPMC10733115
OpenAlexW4390024477

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.