Evidence map›Paper›PMID 38130991›Full record

ArticleFrontiers in oncology2023

Interferon gamma immunoPET imaging to evaluate response to immune checkpoint inhibitors.

Justin B Hackett, Nicholas Ramos, Stephen Barr, Madeline Bross, Nerissa T Viola, Heather M Gibson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Challenges in tracer development for tumor microenvironment (TME) imaging.European journal of nuclear medicine and molecular imaging · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. PET imaging of Aspergillus infection using Zirconium-89 labeled anti-β-glucan antibody fragments.European journal of nuclear medicine and molecular imaging · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Justin B HackettKarmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United States.
Nicholas RamosKarmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United States.
Stephen BarrKarmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United States.
Madeline BrossKarmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United States.
Nerissa T ViolaKarmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United States.
Heather M GibsonKarmanos Cancer Institute, Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United States.
The Barbara Ann Karmanos Cancer Institute · USWayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
TRAINING PROGRAM IN THE BIOLOGY OF CANCERT32CA009531 · NCI · WAYNE STATE UNIVERSITY · PI Larry H Matherly · 1985 to 2026
$5.3M
Delineating Functional Immunity via Image-Guided PETR37CA220482 · NCI · WAYNE STATE UNIVERSITY · PI GIBSON, HEATHER MARIE, VIOLA, NERISSA THERESE · 2018 to 2024
$3.9M
NCI NIH HHS P30 CA022453NCI NIH HHS R37 CA220482NCI NIH HHS T32 CA009531
6 · The paper itself

Abstract

Introduction: We previously developed a Methods: BALB/c mice bearing CT26 colorectal tumors were treated with combined ICI (anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death 1 (PD-1)). The [ Results: We detected significantly higher intratumoral localization of [ Discussion: These results support the use of IFNγ PET as a method to monitor immune activity

Indexed as

immune checkpoint inhibitorsimmunoPET imagingimmunotherapyinterferon gammaradioactive tracer

Identifiers

PMID38130991
PMCPMC10735274
OpenAlexW4389482651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.