Evidence map›Paper›PMID 38130953›Full record

ReviewFrontiers in cell and developmental biology2023

Hippo pathway in intestinal diseases: focusing on ferroptosis.

Hongwei Deng, Qiuting Jia, Xin Ming, Yuxin Sun, Yuxuan Lu, Li Liu, Jun Zhou

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hongwei DengDepartment of Anesthesiology, Southwest Medical University, Luzhou, China.
Qiuting JiaDepartment of Anesthesiology, Southwest Medical University, Luzhou, China.
Xin MingAnesthesiology and Critical Care Medicine Key Laboratory of Luzhou, Luzhou, China.
Yuxin SunAnesthesiology and Critical Care Medicine Key Laboratory of Luzhou, Luzhou, China.
Yuxuan LuDepartment of Anesthesiology, Southwest Medical University, Luzhou, China.
Li LiuDepartment of Anesthesiology, Southwest Medical University, Luzhou, China.
Jun ZhouDepartment of Anesthesiology, Southwest Medical University, Luzhou, China.
Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of intestinal diseases, such as inflammatory bowel disease, gastric cancer, and colorectal cancer, has steadily increased over the past decades. The Hippo pathway is involved in cell proliferation, tissue and organ damage, energy metabolism, tumor formation, and other physiologic processes. Ferroptosis is a form of programmed cell death characterized by the accumulation of iron and lipid peroxides. The Hippo pathway and ferroptosis are associated with various intestinal diseases; however, the crosstalk between them is unclear. This review elaborates on the current research on the Hippo pathway and ferroptosis in the context of intestinal diseases. We summarized the connection between the Hippo pathway and ferroptosis to elucidate the underlying mechanism by which these pathways influence intestinal diseases. We speculate that a mutual regulatory mechanism exists between the Hippo pathway and ferroptosis and these two pathways interact in several ways to regulate intestinal diseases.

Indexed as

crosstalkferroptosisHippo pathwayintestinal diseasesmechanisms

Identifiers

PMID38130953
PMCPMC10734691
OpenAlexW4389392844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.