ArticleJournal of translational internal medicine2023
Global lineage evolution pattern of sars-cov-2 in Africa, America, Europe, and Asia: A comparative analysis of variant clusters and their relevance across continents.
Article in Journal of translational internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A century of emergence: trends and patterns in human viral pathogens, 1900-2024, a systematic review.BMC infectious diseases · 2025Pooled it
- Enriching Public Pathogen Genomic Records With Patient Metadata: Quantitative Study and Exploratory Case Analysis.JMIR bioinformatics and biotechnology · 2026Article
- Prevalence and biomarker profiles of HBV/HDV coinfection and occult HBV infection among patients attending Bimbilla Hospital, Northern Ghana.BMC infectious diseases · 2026Article
- Hepatitis B burden in the Middle East and North Africa region, 1990-2030: trends, projections, and age-period-cohort analysis.BMC infectious diseases · 2026Article
- Efficacy of glucocorticoid therapy for severe jaundice patients with drug-induced liver injury or hepatitis B virus-related acute-on-chronic liver failure: a respectively observational study.BMC infectious diseases · 2026Observational
- Illness trajectory in the longer term after hospitalisation for COVID-19: a prospective, multicentre cohort study.BMC infectious diseases · 2026Observational
- Association of PD-1BMC infectious diseases · 2026Article
- Genomic diversity of SARS-CoV-2 carriage in a cohort of schoolchildren in Côte d'ivoire during COVID-19 pandemics: insights from pre-delta emergence.BMC infectious diseases · 2026Article
- Post-pandemic shifts in pediatric respiratory pathogens and co-infection dynamics in Xi'an and surrounding areas: a large-scale retrospective study from 2021 to 2025.BMC infectious diseases · 2025Article
- Nutritional and inflammatory biomarkers for COVID-19 susceptibility: a focus on vitamin D, potassium, and hematological indices.BMC infectious diseases · 2025Article
- High frequency of antibiotic administration for COVID-19 patients in Syria and its associations with mortality and complications.BMC infectious diseases · 2025Observational
- Seroprevalence and associated factors of Helicobacter pylori infection among young adults in the West Bank, Palestine.BMC infectious diseases · 2025Article
- Impact of obesity on COVID-19 CoronaVac and ChAdOx1-S vaccine efficacy.BMC infectious diseases · 2025Article
- Plasma proteomic signatures in HIV-infected individuals post-SARS-CoV-2 infection.BMC infectious diseases · 2025Article
- Clinical risk factors and a predictive nomogram for mechanical ventilation in pediatric patients with infection-related plastic bronchitis.BMC infectious diseases · 2025Article
- A novel model for predicting the risk of liver cirrhosis in people living with HIV/HBV coinfection: a study based on proteomic analysis.BMC infectious diseases · 2025Article
- Risk factors analysis for progression to severe hepatitis in acute hepatitis E: a retrospective study of 146 hospitalized cases.BMC infectious diseases · 2025Article
- Enhancing battery thermal management system using the emulsion of encapsulated phase change material and water in a mini helical tube.Scientific reports · 2025Article
- Tracking the pandemic through molecular and sequencing tools: a story of SARS- CoV-2 over five years, lessons learned, and further directions.BMC infectious diseases · 2025Article
- SARS-CoV-2 reinfection in interstitial lung disease patients and its association with clinical deterioration: a two-year prospective cohort study.BMC infectious diseases · 2025Article
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10 authors.
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Abstract
Objective: The objective of this study is to provide a comparative analysis of variant clusters and their relevance across Africa, America, Europe, and Asia, in order to understand the evolutionary patterns of the virus across different regions and to inform the development of targeted interventions and genomic surveillance eforts. Methods: The study analyzed the global lineage evolution pattern of 74, 075 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from 32 countries across four continents, focusing on variant clusters and their relevance across regions. Variants were weighted according to their hierarchical level. The correlation between variants was visualized through Dimensionality reduction analysis and Pairwise Pearson's correlation. We presented a reconstructed phylogenetic tree based on correlation analysis and variant weights. Results: The analysis revealed that each continent had distinct variant clusters and different evolutionary patterns. The Americas had two clustered variants before lineage divergence and a downstream confluence lineage, Europe had bifurcation into two global lineages with an early occurrence of certain cluster while Asia had a downstream confluence of two large lineages diverging by two distinct clusters. Based on the cluster patterns of shared variants of the SARS-CoV-2 virus, Africa demonstrated a relatively clear distinction among three distinct regions. Conclusions: The study provides insights into the evolutionary patterns of SARS-CoV-2 and highlights the importance of international collaboration in tracking and responding to emerging variants. The study found that the global pandemic was driven by Omicron variants that evolved with significant differences between countries and regions, and with different patterns across continents.
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