Evidence map›Paper›PMID 38130530›Full record

ArticleCureus2023

A Multifaceted Presentation of Xerophthalmia in Autistic Patients.

Annuar Zaki Azmi, Sylves Patrick, Mohamad Israk B Isa, Shuaibah Ab Ghani

Abstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Annuar Zaki AzmiDepartment of Paediatric Ophthalmology, Sabah Women and Children Hospital, Kota Kinabalu, MYS.
Sylves PatrickDepartment of Ophthalmology, Faculty of Medicine and Health Sciences, University Malaysia Sabah, Kota Kinabalu, MYS.
Mohamad Israk B IsaDepartment of Paediatric Ophthalmology, Sabah Women and Children Hospital, Kota Kinabalu, MYS.
Shuaibah Ab GhaniDepartment of Ophthalmology, Faculty of Medicine and Health Sciences, University Malaysia Sabah, Kota Kinabalu, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the manifestations of vitamin A deficiency (VAD) in three children with underlying autism of different stages. These children were under developmental paediatrician follow-up for autism, and the VAD was not detected until these children presented to Ophthalmology screening for varying stages of signs and symptoms. On further assessment, all of our patients have VAD secondary to poor dietary intake, as autistic patients are associated with having selective eating habits. In our case series, we discuss the spectrum of xerophthalmia presentations, which can be mild and can manifest as punctate epithelial erosions to the more blinding complications at the advanced stage of the disease, mainly irreversible optic neuropathy. The primary management is to address the dietary routine coupled with systemic administration of vitamin A.

Indexed as

autismkeratomalaciavitamin a deficiencyxerophthalmiaxerosis

Identifiers

PMID38130530
PMCPMC10734353

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.