Evidence map›Paper›PMID 38130338›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Dairy and gluten in disease activity in multiple sclerosis.

Isabel A Temperley, Alexandra N Seldon, Madeline Aw Reckord, Claudia A Yarad, Farihah T Islam, Kerith Duncanson, Rodney A Lea, Jeannette Lechner-Scott, Vicki E Maltby

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Isabel A TemperleySchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.ORCID https://orcid.org/0000-0001-7079-5708
Alexandra N SeldonSchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.ORCID https://orcid.org/0000-0002-5514-2335
Madeline Aw ReckordSchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Claudia A YaradSchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Farihah T IslamSchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Kerith DuncansonCentre of Research Excellence in Digestive Health, University of Newcastle, Callaghan, NSW, Australia.
Rodney A LeaHunter Medical Research Institute, New Lambton Heights, NSW, Australia.
Jeannette Lechner-ScottSchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Vicki E MaltbySchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.ORCID https://orcid.org/0000-0002-3785-4742
University of Newcastle Australia · AUJohn Hunter Hospital · AUQueensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Many diets promoted specifically for multiple sclerosis have been suggested to improve disease activity. Dairy and gluten are two components for which the recommendations vary between these diets. Existing research into the association between these dietary components and disease activity has been conflicting. Objective: To explore the relationship between dairy and gluten intake and disease activity in multiple sclerosis over a 2-year period, using no evidence of disease activity (NEDA) 3 status. Methods: 186 participants' dairy and gluten intake was retrospectively estimated over 2 years using a dairy and gluten dietary screener. Estimated dairy and gluten intake was compared to disease activity, indicated by no evidence of disease activity 3 status, and quality of life, assessed by the Multiple Sclerosis International Quality of Life (MusiQoL) questionnaire. Results: No significant association was found between mean estimated dairy or gluten intake and NEDA 3 status ( Conclusion: Whilst we cannot rule out modest benefits due to our small sample size, we found that neither dairy nor gluten intake was associated with disease activity or quality of life in this study.

Indexed as

dairydietdisease activityglutenMultiple sclerosisMultiple Sclerosis International Quality of Lifeno evidence of disease activity 3quality of life

Identifiers

PMID38130338
PMCPMC10734333
OpenAlexW4390033745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.