ArticleLaryngoscope investigative otolaryngology2023
Clinical factors influencing olfactory performance in patients with persistent COVID-19 smell loss longer than 1 year.
Article in Laryngoscope investigative otolaryngology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The Effectiveness of Functional Septorhinoplasty in Improving COVID-19-related Olfactory Dysfunction.Facial plastic surgery : FPS · 2026Article
- Improved Nasal Airflow Is Associated With Olfactory Recovery in a Large Population of Patients With COVID-19-Related Olfactory Dysfunction.Laryngoscope investigative otolaryngology · 2025Article
- Cognitive and Psychological Symptoms in Post-COVID-19 Condition: A Systematic Review of Structural and Functional Neuroimaging, Neurophysiology, and Intervention Studies.Archives of rehabilitation research and clinical translation · 2025Review
- Long-term self-reported symptoms and psychophysical tests in COVID-19 subjects experiencing persistent olfactory dysfunction: a 4-year follow-up study.Frontiers in neural circuits · 2025Article
- Objective and Subjective Outcomes Following Radiofrequency of Inferior Turbinates in Patients with Sleep-Disordered Breathing.Diagnostics (Basel, Switzerland) · 2024Article
- Clinical factors influencing olfactory performance in patients with persistent COVID-19 smell loss longer than 1 year.Laryngoscope investigative otolaryngology · 2023Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Factors affecting persistence of COVID-19-related olfactory dysfunction (OD) remain partially unknown. We aim to evaluate the clinical factors which could influence olfactory performance in patients with persistent COVID-19-related smell loss. Methods: A retrospective analysis of 100 patients with persistent COVID-19-related OD was performed between October 2020 and December 2022 at a single-center long-COVID smell clinic. All subjects underwent smell assessment using Sniffin' Sticks (S'S) extended test, nasal endoscopy, nasal airflow evaluation (peak nasal inspiratory flow [PNIF]), allergy test (skin prick test [SPT]) for common aeroallergens, MRI of the head and patient-reported outcome measures (PROMs-VAS, SF-36, Short QOD-NS, SNOT-22). Based on S'S score, subjects were divided into normosmics (TDI ≥ 30.75) and dysosmics (TDI < 30.75). Results: The median age was 42 years and the median length of patient-reported OD was 1.4 years. 20 patients (20.0%) were normosmic at the time of S'S assessment. Dysosmic patients were found to have significantly lower scores at the SF-36 health domains for energy/fatigue ( Conclusions: Impairment of nasal airflow and sensitivity to aeroallergens can negatively affect olfactory performance in COVID-19-related OD. Long-COVID smell loss deeply affects QoL although recovery of olfaction can bring it back to a normal range. Level of Evidence: IV.
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