Evidence map›Paper›PMID 38130208›Full record

ArticleJournal of primary care & community health

Higher Hepatitis C Cure Rates in a Patient-Centered Medical Home Compared to Specialist Care.

Jonathan Hughes, Nicholas Hodge, Amber Shadoan, Courtney Ellis, Ben Turner, Craig Glass

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Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jonathan HughesAscension Saint Thomas Rutherford, Murfreesboro, TN, USA.ORCID 0000-0002-2595-8835
Nicholas HodgeAscension Saint Thomas Rutherford, Murfreesboro, TN, USA.
Amber ShadoanUniversity of Tennessee Nashville Family Medicine Residency Program, Nashville, TN, USA.
Courtney EllisUniversity of Tennessee College of Pharmacy, Knoxville, TN, USA.
Ben TurnerAscension Saint Thomas Rutherford, Murfreesboro, TN, USA.
Craig GlassUniversity of Tennessee Nashville Family Medicine Residency Program, Nashville, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe new era of direct-acting antivirals (DAAs) against the hepatitis C virus (HCV) has led many primary care clinicians to begin treating HCV. Nevertheless, many patients are referred to specialists due to comorbidities, care complexities, and knowledge gaps of the primary care provider. We compared clinical outcomes for patients treated within a Family Medicine Residency Program (FMRP) affiliated patient-centered medical home (PCMH) with those referred to a specialist.

methodsFollowing didactic education and development of practice resources we conducted a single-center quasi-experimental study of adults with HCV referred for treatment either internally or externally to a specialist between January 2019 and December 2020. The primary outcome was the number of patients with a sustained virologic response at 12 weeks after treatment (SVR12), utilizing an intention-to-treat analysis.

resultsDuring the study period 107 patients were assessed by the PCMH, of whom 24 were deemed not a good candidate for treatment. Of the 83 patients referred for treatment, 36 patients were referred externally and 47 were treated internally. While the rate of SVR12 was 100% for both groups when analyzed per protocol (ie, only patients who completed treatment and attended all follow-ups), the rate of SVR12 was 31% for patients referred externally and 62% for patients treated internally when analyzed by intention to treat (relative risk [RR] 2.02, 95% CI 1.18-3.47,

conclusionsFollowing education and creation of practice resources, achievement of SVR12 among patients with HCV treated by an internal interdisciplinary family medicine team was superior to those who were externally referred. This was primarily attributable to differences in follow-up rates.

Indexed as

Hepatitis CHepatitis C, ChronicAdultAntiviral AgentsHepacivirusHumansPatient-Centered CareTreatment OutcomeAntiviral Agentsdirect-acting antiviralfamily medicinehepatitis Cpatient-centered medical homeSVR12

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