ArticleAnnals of clinical and translational neurology2024
Cognitive and emotional predictors of quality of life and functioning after COVID-19.
Article in Annals of clinical and translational neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Health-related quality of life in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post COVID-19 Condition: a systematic review.Journal of translational medicine · 2025Pooled it
- Cognitive functioning in young adults after mild COVID-19: A case-control study from Iran.IBRO neuroscience reports · 2025Article
- Brain Microstructural Alterations in Children Post-COVID-19 Infection Through VBM, SBM, and Structural Covariance Network Analysis.Brain and behavior · 2025Article
- Beyond COVID-19 Infection: Cognitive and Emotional Pathways Between Posttraumatic Stress, Rumination, and Quality of Life in Hospitalized Patients.Healthcare (Basel, Switzerland) · 2025Article
- Staying Safe for the Long Haul: A Health Belief Model Analysis of COVID-19 Preventive Behaviors Through the Lens of Long COVID.Clinical nursing research · 2025Article
- Article
- The Influence of the COVID-19 Pandemic on the Sexual Lives of Polish Young Adults.Journal of clinical medicine · 2024Article
- Factors associated with cognitive impairment and the quality-of-life among COVID-19 survivors working as healthcare workers.Narra J · 2024Article
- Poor sleep quality may trigger cognitive deficits after recovery from COVID-19.Frontiers in psychology · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveA long-term decline in health-related quality of life (HRQoL) has been reported after coronavirus disease 2019 (COVID-19). Studies with people with persistent symptoms showed inconsistent outcomes. Cognition and emotion are important determinants in HRQoL, but few studies have examined their prognostic significance for HRQoL and functionality in post-COVID patients with persisting symptoms. We aimed to describe QoL, HRQoL, and functioning in individuals post-COVID with varying COVID-19 severities and to investigate the predictive value of cognitive and emotional variables for QoL, HRQoL, and functioning.
methodsIn total, 492 participants (398 post-COVID and 124 healthy controls) underwent a neurobehavioral examination that included assessments of cognition, mood, QoL/HRQoL (WHOQOL-BREF, EQ-5D), and functioning (WHODAS-II). Analysis of covariance and linear regression models were used to study intergroup differences and the relationship between cognitive and emotional variables and QoL and functioning.
resultsThe Physical and Psychological dimensions of WHOQoL, EQ-5D, and WHODAS Cognition, Mobility, Life Activities, and Participation dimensions were significantly lower in post-COVID groups compared with a control group. Regression models explaining 23.9%-53.9% of variance were obtained for the WHOQoL-BREF dimensions and EQ-5D, with depressive symptoms, post-COVID symptoms, employment status, income, and mental speed processing as main predictors. For the WHODAS, models explaining 17%-60.2% of the variance were obtained. Fatigue, depressive symptoms, mental speed processing, and post-COVID symptoms were the main predictors.
interpretationQoL/HRQoL and functioning after COVID-19 in individuals with persistent symptoms were lower than in non-affected persons. Depressive symptoms, fatigue, and slower mental processing speed were predictors of lower QoL/HRQoL and functioning.
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