Evidence map›Paper›PMID 38129899›Full record

ArticleJournal of medical case reports2023

Hepatic and lung methotrexate-associated polymorphic lymphoproliferative disorders arising during postoperative follow-up of renal cell carcinoma: a case report.

Yoshi Miyamoto, Chihiro Kawasoe, Kaoru Ito, Nobuyuki Oguri, Takaya Murashima, Toyoharu Kamibeppu, Takahiro Nagai, Hiroki Takamori, Toshio Kamimura, Shoichiro Mukai and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yoshi MiyamotoDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Chihiro KawasoeDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Kaoru ItoDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Nobuyuki OguriDepartment of Diagnostic Pathology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Takaya MurashimaDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Toyoharu KamibeppuSection of Urology, Koga General Hospital, Miyazaki, Japan.
Takahiro NagaiDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Hiroki TakamoriDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Toshio KamimuraDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Shoichiro MukaiDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan. syoichiro_mukai@med.miyazaki-u.ac.jp.ORCID http://orcid.org/0000-0002-1678-8619
Yuichiro SatoDepartment of Diagnostic Pathology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Toshiyuki KamotoDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
University of Miyazaki · JPUniversity of Miyazaki Hospital · JPKoga Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMethotrexate induces lymphoproliferative disorders on rare occasions; however, its pathogenesis remains unknown. A clinical diagnosis based on imaging studies alone is often difficult. CASE PRESENTATION: A 57-year-old Japanese woman was referred to our department for the evaluation of multiple lung and hepatic nodules that developed during methotrexate treatment for rheumatoid arthritis. Since she had a history of nephrectomy for localized renal cell carcinoma, multiple lung and hepatic metastases were initially considered. However, pathological diagnosis of the lung nodules (needle biopsy) revealed methotrexate-associated polymorphic-type lymphoproliferative disorders. After methotrexate discontinuation, continuous smooth shrinkage of the lung and liver lymphoproliferative disorders was observed.

conclusionMethotrexate-associated lymphoproliferative disorders should be considered in the event of newly appearing neoplastic lesions, even during follow-up for renal cell carcinoma, if methotrexate is being administered.

Indexed as

Antirheumatic AgentsCarcinoma, Renal CellEpstein-Barr Virus InfectionsKidney NeoplasmsLymphoproliferative DisordersEast Asian PeopleFemaleFollow-Up StudiesHumansLiverLungMethotrexateMiddle AgedAntirheumatic AgentsMethotrexateEpstein–Barr virusMethotrexate associated lymphoproliferative disordersPolymorphic lymphoproliferative disordersRenal cell carcinoma

Identifiers

PMID38129899
PMCPMC10740260
OpenAlexW4390080810

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.