Evidence map›Paper›PMID 38129894›Full record

Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2023

Favourable neurological outcome following paediatric out-of-hospital cardiac arrest: a retrospective observational study.

Alexander Fuchs, Deliah Bockemuehl, Sabrina Jegerlehner, Christian P Both, Evelien Cools, Thomas Riva, Roland Albrecht, Robert Greif, Martin Mueller, Urs Pietsch

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. RECOVER Guidelines: First Aid in Dogs and Cats. Evidence and Knowledge Gap Analysis With Treatment Recommendations.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2026
    Article
  2. RECOVER Guidelines: First Aid for Dogs and Cats. Clinical Guidelines.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2026
    Article
  3. Observational
  4. Article
  5. Age-specific considerations in aetiology of paediatric out-of-hospital cardiac arrest.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Article
  6. Favourable neurological outcome following paediatric out-of-hospital cardiac arrest: authors' reply.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024
    Article
  7. Paediatric cardiac arrest prognostication in the context of a HEMS service.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Alexander Fuchs *Department of Anaesthesiology and Pain Medicine, Bern University Hospital, Inselspital, University of Bern, Freiburgstrasse, Bern, 3010, +41 31 664 14 65, Switzerland. Alexander.Fuchs@insel.ch.ORCID http://orcid.org/0000-0001-7188-1683
Deliah Bockemuehl *Department of perioperative Intensive Care Medicine, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.ORCID http://orcid.org/0009-0004-3616-3036
Sabrina JegerlehnerDepartment of Emergency Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-0868-0608
Christian P BothDepartment of Anaesthesiology, Children's Hospital Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-1289-4924
Evelien CoolsSwiss Air-Ambulance (Rega), Zurich, Switzerland.ORCID http://orcid.org/0000-0002-9607-7277
Thomas RivaDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, Inselspital, University of Bern, Freiburgstrasse, Bern, 3010, +41 31 664 14 65, Switzerland.ORCID http://orcid.org/0000-0003-1297-3427
Roland AlbrechtSwiss Air-Ambulance (Rega), Zurich, Switzerland.
Robert GreifUniversity of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-0160-2073
Martin Mueller *Department of Emergency Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-4067-7174
Urs Pietsch *Swiss Air-Ambulance (Rega), Zurich, Switzerland.ORCID http://orcid.org/0000-0001-6957-2638
University of Bern · CHUniversity of St.Gallen · CHSigmund Freud Privatuniversität Wien · ATUniversity Children's Hospital Zurich · CHUniversity of Geneva · CH

Funding

Inselspital, Universitätsspital Bern Inselspital, Universitätsspital Bern
6 · The paper itself

Abstract

backgroundOut-of-hospital cardiac arrest (OHCA) in children is rare and can potentially result in severe neurological impairment. Our study aimed to identify characteristics of and factors associated with favourable neurological outcome following the resuscitation of children by the Swiss helicopter emergency medical service. MATERIALS AND

methodsThis retrospective observational study screened the Swiss Air-Ambulance electronic database from 01-01-2011 to 31-12-2021. We included all primary missions for patients ≤ 16 years with OHCA. The primary outcome was favourable neurological outcome after 30 days (cerebral performance categories (CPC) 1 and 2). Multivariable linear regression identified potential factors associated with favourable outcome (odd ratio - OR).

resultsHaving screened 110,331 missions, we identified 296 children with OHCA, which we included in the analysis. Patients were 5.0 [1.0; 12.0] years old and 61.5% (n = 182) male. More than two-thirds had a non-traumatic OHCA (67.2%, n = 199), while 32.8% (n = 97) had a traumatic OHCA. Thirty days after the event, 24.0% (n = 71) of patients were alive, 18.9% (n = 56) with a favourable neurological outcome (CPC 1 n = 46, CPC 2 n = 10). Bystander cardiopulmonary resuscitation (OR 10.34; 95%CI 2.29-51.42; p = 0.002) and non-traumatic aetiology (OR 11.07 2.38-51.42; p = 0.002) were the factors most strongly associated with favourable outcome. Factors associated with an unfavourable neurological outcome were initial asystole (OR 0.12; 95%CI 0.04-0.39; p < 0.001), administration of adrenaline (OR 0.14; 95%CI 0.05-0.39; p < 0.001) and ongoing chest compression at HEMS arrival (OR 0.17; 95%CI 0.04-0.65; p = 0.010).

conclusionIn this study, 18.9% of paediatric OHCA patients survived with a favourable neurologic outcome 30 days after treatment by the Swiss helicopter emergency medical service. Immediate bystander cardiopulmonary resuscitation and non-traumatic OHCA aetiology were the factors most strongly associated with a favourable neurological outcome. These results underline the importance of effective bystander and first-responder rescue as the foundation for subsequent professional treatment of children in cardiac arrest.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesEmergency RespondersOut-of-Hospital Cardiac ArrestChildChild, PreschoolFemaleHumansInfantMaleRegistriesRetrospective StudiesAdvanced life supportChain-of-survivalChildrenHEMSOut-of-hospital Cardiac ArrestResuscitation

Identifiers

PMID38129894
PMCPMC10734091
OpenAlexW4390052794

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.