Evidence map›Paper›PMID 38129853›Full record

ReviewJournal of nanobiotechnology2023

Exosome-based engineering strategies for the diagnosis and treatment of oral and maxillofacial diseases.

Jianing Ren, Xuan Jing, Yingyu Liu, Jinrong Liu, Xiao Ning, Mingrui Zong, Ran Zhang, Huaiyi Cheng, Jiayu Cui, Bing Li and 1 more

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Exosomes in the Chemoresistance of Glioma: Key Point in Chemoresistance.Journal of cellular and molecular medicine · 2025
    Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jianing Ren *Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Xuan Jing *Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Yingyu LiuShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Jinrong LiuShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Xiao NingShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Mingrui ZongShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Ran ZhangShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Huaiyi ChengShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Jiayu CuiShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Bing LiShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China. libing1975vip@163.com.
Xiuping WuShanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China. wxp1666@sxmu.edu.cn.

Funding

Four "Batches" Innovation Project of Invigorating Medical through Science and Technology of Shanxi Province 2023XM013Key national science and technology cooperation project of Shanxi Provincial Department of Science and Technology 202204041101004Key Research and Development Plan of Shanxi Province 202102130501002Science and technology innovation project of colleges and universities in Shanxi Province 2022L166Scientific Research Project for Returned Overseas Professionals of Shanxi Province 2022-120Shanxi Province Basic Research Plan 202203021222256This work is supported by Science and Technology Innovation Leader and Key Talent Team Project of Shanxi Province 202204051002034
6 · The paper itself

Abstract

Oral and maxillofacial diseases are one of the most prevalent diseases in the world, which not only seriously affect the health of patients' oral and maxillofacial tissues, but also bring serious economic and psychological burdens to patients. Therefore, oral and maxillofacial diseases require effective treatment. Traditional treatments have limited effects. In recent years, nature exosomes have attracted increasing attention due to their ability to diagnose and treat diseases. However, the application of nature exosomes is limited due to low yield, high impurities, lack of targeting, and high cost. Engineered exosomes can be endowed with better comprehensive therapeutic properties by modifying exosomes of parent cells or directly modifying exosomes, and biomaterial loading exosomes. Compared with natural exosomes, these engineered exosomes can achieve more effective diagnosis and treatment of oral and maxillary system diseases, and provide reference and guidance for clinical application. This paper reviews the engineering modification methods of exosomes and the application of engineered exosomes in oral and maxillofacial diseases and looks forward to future research directions.

Indexed as

ExosomesBiocompatible MaterialsHumansBiocompatible MaterialsDiagnosisEngineeringExosomesOral and maxillofacial systemTreatment

Identifiers

PMID38129853
PMCPMC10740249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.