Evidence map›Paper›PMID 38129792›Full record

ArticleBMC cancer2023

Incidence and pattern of childhood cancer in Addis Ababa, Ethiopia (2012-2017).

Amanuel Belay, Ahmed Ali, Wondimu Ayele, Mathewos Assefa, Ahmedin Jemal, Eva J Kantelhardt

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Amanuel BelayCentre for Innovative Drug Development and Therapeutic Trials for Africa (CDT- Africa), Addis Ababa University, Addis Ababa, Ethiopia. amanbelays@gmail.com.
Ahmed AliSchool of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Wondimu AyeleSchool of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Mathewos AssefaDepartment of Oncology, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Ahmedin JemalAmerican Cancer Society, Atlanta, GA, USA.
Eva J KantelhardtDepartment of Gynecology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Addis Ababa University · ETAmerican Cancer Society · USMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is becoming a major public health problem globally and a leading cause of death in children in developed countries. However, little is known about the epidemiology of childhood cancer in Ethiopia. This study, therefore, assessed childhood cancer incidence patterns in Addis Ababa using the Addis Ababa city population-based cancer registry data from 2012 to 2017.

methodsInvasive cancer cases diagnosed in ages 0-14 years from 2012 to 2017 were obtained from the Addis Ababa City population-based Cancer Registry. Cases were grouped according to the International Classification of Childhood Cancer, 3rd edition (ICCC-3) based on morphology and primary anatomic site. Age-standardized incidence rates (ASR) were calculated by the direct method using the world standard population.

resultsThe overall average annual incidence rate during 2012-2017 in children was 84.6 cases per million, with rates higher in boys (98.97 per million) than in girls (69.7 per million). By age, incidence rates per million increased from 70.8 cases in ages 0-4 years to 88.4 cases in ages 5-9 years to 110.0 cases 10-14 years. Leukaemia was the most common childhood cancer in both boys (29.1%) and girls (26.8%), followed by lymphoma in boys (24.7%) and renal tumours (13.1%) in girls. The overall cancer incidence rate decreased from 87.02 per million in 2012 to 51.07 per million in 2017.

conclusionThe burden of childhood cancer is considerably high in Addis Ababa. The observed distribution of childhood cancer in Addis Ababa differs from other African countries. This study highlights the need for further research and understanding of the variations in cancer patterns and risk factors across the region.

Indexed as

Kidney NeoplasmsLymphomaChildChild, PreschoolEthiopiaFemaleHumansIncidenceInfantInfant, NewbornMaleRisk FactorsAddis AbabaChildhood cancerEthiopiaIncidencePattern

Identifiers

PMID38129792
PMCPMC10734044
OpenAlexW4390052107

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.