Evidence map›Paper›PMID 38129779›Full record

ArticleBMC immunology2023

TRPV1

Changyu Huang, Yang Chen, Yuanqing Cai, Haiqi Ding, Jiaoying Hong, Shan You, Yiming Lin, Hongxin Hu, Yongfa Chen, Xueni Hu and 8 more

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Skin innervation and itsFrontiers in cellular neuroscience · 2026
    Review
  5. Review
  6. Pathogens (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Review
  9. TRPA1 InfluencesInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Changyu Huang *Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Yang Chen *Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Yuanqing Cai *Department of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Haiqi DingDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Jiaoying HongDepartment of Anesthesiology, The Second Hospital of Nan'an, Quanzhou, Fujian, China.
Shan YouFujian Medical University, Fuzhou, Fujian, China.
Yiming LinDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Hongxin HuDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Yongfa ChenDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Xueni HuDepartment of Laboratory Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Yanshu ChenDepartment of Laboratory Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Ying HuangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Chaofan ZhangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Yunzhi LinDepartment of Stomatology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Zida HuangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Wenbo LiDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China.
Wenming ZhangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China. zhangwm0591@fjmu.edu.cn.
Xinyu FangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350212, China. fangxinyu0417@fjmu.edu.cn.
First Affiliated Hospital of Fujian Medical University · CNFujian Medical University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

Natural Science Foundation of Fujian Province 2023J05131the National Science Foundation Grant of China 82072458the Natural Science Foundation of Fujian Province 2022J011457the Natural Science Foundation of Fujian Province 2022J01219
6 · The paper itself

Abstract

backgroundThe interaction between the nervous system and the immune system can affect the outcome of a bacterial infection. Staphylococcus aureus skin infection is a common infectious disease, and elucidating the relationship between the nervous system and immune system may help to improve treatment strategies.

resultsIn this study, we found that the local release of calcitonin gene-related peptide (CGRP) increased during S. aureus skin infection, and S. aureus could promote the release of CGRP from transient receptor potential cation channel subfamily V member 1 (TRPV1

conclusionsIn S. aureus skin infection, TRPV1

Indexed as

Calcitonin Gene-Related PeptideStaphylococcus aureusMacrophagesNeuronsNeutrophil InfiltrationCalcitonin Gene-Related PeptideCalcitonin gene-related peptideMacrophageNeutrophileNociceptor neuronSkin infectionStaphylococcus aureus

Identifiers

PMID38129779
PMCPMC10740264
OpenAlexW4390060653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.