Evidence map›Paper›PMID 38129709›Full record

ArticleCell biochemistry and biophysics2024

Hypoxia Potentiated Lung Cancer Cell Migration and Invasion by up-regulating HIF1α/JAK2/STAT3 Axis and Activating MMP13 Transcription.

Xiaoju Cheng, Damin Liang, Xiaoqian Li, Chengmin Deng, Meng Ye, Jiao Yang, Yurui Liu, Kaifeng Wu, Jie Wu, Peng Tian

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoju Cheng *Scientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Damin Liang *Department of Medical Technology, Zunyi Medical College, Zunyi, 563003, China.
Xiaoqian LiScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Chengmin DengScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Meng YeScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Jiao YangScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Yurui LiuScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Kaifeng WuScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China.
Jie WuScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China. zhiwenwujie@163.com.
Peng TianScientific Research Center, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, 563003, China. tianpeng52@163.com.ORCID http://orcid.org/0000-0001-8380-9646
Zunyi Medical University · CN

Funding

the Joint project of Zunyi Science and Technology Bureau No. ZSKH-SZ [2018]41, ZSKH-HZ [2020]117, ZSKH-HZ [2022]43, ZSKH-HZ [2022]151 and YKQ [2021]8the Science and Technology Plan Project of Guizhou Health Commission No. gzwjkj2019-1-045the Science and Technology Plan Project of Guizhou Province No. ZK [2021]494 and ZC [2020]4Y12
6 · The paper itself

Abstract

Excessive aggressive migration and invasion are important factors that increase the mortality of cancer patients. Matrix metalloproteinase 13 (MMP13) expression is positively correlated with lung cancer malignancy. However, the mechanism underlying an elevated MMP13 expression is not clearly defined. In this study, we demonstrated that hypoxia induced by CoCl

Indexed as

Adenocarcinoma of LungLung NeoplasmsCell Line, TumorCell MovementCell ProliferationHumansHypoxiaJanus Kinase 2Matrix Metalloproteinase 13STAT3 Transcription FactorJAK2 protein, humanJanus Kinase 2Matrix Metalloproteinase 13MMP13 protein, humanSTAT3 protein, humanSTAT3 Transcription FactorHypoxiaLung adenocarcinomaMigration and invasionMMP13 transcriptionSTAT3

Identifiers

PMID38129709
OpenAlexW4390062546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.